PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31846070-5 2020 Extensive in vitro and preclinical research has demonstrated that niclosamide was found to exert potent anticancer and anti-inflammatory properties by targeting STAT3, p65 NF-kappaB, and NFATc-1 signaling paradigm with minimal host toxicity. Niclosamide 66-77 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 168-171 31846070-10 2020 Additionally, our results provided a preclinical rationale in imiquimod (IMQ)-induced BALB/c mouse model, where niclosamide diligently mitigated the IMQ-induced epidermal hyperplasia and inflammation by downregulating STAT3, p65 NF-kappaB, and NFATc-1 transcription factors along with Akt, Ki-67, and ICAM-1 protein expression. Niclosamide 112-123 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 225-228 27492973-0 2017 Anthelmintic Niclosamide Disrupts the Interplay of p65 and FOXM1/beta-catenin and Eradicates Leukemia Stem Cells in Chronic Myelogenous Leukemia. Niclosamide 13-24 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 51-54 27492973-12 2017 CONCLUSIONS: Interaction of p65 with FOXM1/beta-catenin is critical in CML and its disruption by niclosamide eradicates LSCs. Niclosamide 97-108 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 28-31 27535961-5 2016 When the recipient mice were treated with niclosamide for 3 weeks, niclosamide reduced the size of endometriotic implants with inhibition of cell proliferation, and inflammatory signaling including RELA (NFKB) and STAT3 activation, but did not alter expression of steroid hormone receptors. Niclosamide 42-53 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 198-202 27535961-5 2016 When the recipient mice were treated with niclosamide for 3 weeks, niclosamide reduced the size of endometriotic implants with inhibition of cell proliferation, and inflammatory signaling including RELA (NFKB) and STAT3 activation, but did not alter expression of steroid hormone receptors. Niclosamide 67-78 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 198-202