PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26068521-0	2016	Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1.	Niclosamide	36-47	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	171-177	
26068521-11	2016	Although seven UGT enzymes were able to catalyze glucuronidation of niclosamide, UGT1A1 and 1A3 were the enzymes showed the highest metabolic activities.	Niclosamide	68-79	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	81-95	
26068521-12	2016	Activity correlation analyses demonstrated that UGT1A1 played a predominant role in hepatic glucuronidation of niclosamide, whereas the role of UGT1A3 was negligible.	Niclosamide	111-122	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	48-54	
26068521-14	2016	In conclusion, niclosamide was subjected to efficient metabolic reactions hydroxylation and glucuronidation, wherein CYP1A2 and UGT1A1 were the main contributing enzymes, respectively.	Niclosamide	15-26	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	128-134