PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29257330-0	2018	Niclosamide enhances the cytotoxic effect of cisplatin in cisplatin-resistant human lung cancer cells via suppression of lung resistance-related protein and c-myc.	Niclosamide	0-11	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	157-162	
30143678-0	2018	The Antihelminthic Niclosamide Inhibits Cancer Stemness, Extracellular Matrix Remodeling, and Metastasis through Dysregulation of the Nuclear beta-catenin/c-Myc axis in OSCC.	Niclosamide	19-30	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	155-160	
30143678-5	2018	These anticancer activities of niclosamide were similar to those caused by interference with nuclear beta-catenin/c-Myc expression using the siRNA transfection.	Niclosamide	31-42	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	114-119	
30635359-8	2019	Interestingly, niclosamide is a less effective inhibitor of Wnt-responsive genes (beta-catenin, c-Myc, and Survivin) in the niclosamide-resistant cells than in the niclosamide-sensitive cells, suggesting that deficient autophagy induction by niclosamide compromises the effect of niclosamide on Wnt signaling.	Niclosamide	15-26	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	96-101	
30635359-8	2019	Interestingly, niclosamide is a less effective inhibitor of Wnt-responsive genes (beta-catenin, c-Myc, and Survivin) in the niclosamide-resistant cells than in the niclosamide-sensitive cells, suggesting that deficient autophagy induction by niclosamide compromises the effect of niclosamide on Wnt signaling.	Niclosamide	124-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	96-101	
30635359-8	2019	Interestingly, niclosamide is a less effective inhibitor of Wnt-responsive genes (beta-catenin, c-Myc, and Survivin) in the niclosamide-resistant cells than in the niclosamide-sensitive cells, suggesting that deficient autophagy induction by niclosamide compromises the effect of niclosamide on Wnt signaling.	Niclosamide	124-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	96-101	
30635359-8	2019	Interestingly, niclosamide is a less effective inhibitor of Wnt-responsive genes (beta-catenin, c-Myc, and Survivin) in the niclosamide-resistant cells than in the niclosamide-sensitive cells, suggesting that deficient autophagy induction by niclosamide compromises the effect of niclosamide on Wnt signaling.	Niclosamide	124-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	96-101	
30635359-8	2019	Interestingly, niclosamide is a less effective inhibitor of Wnt-responsive genes (beta-catenin, c-Myc, and Survivin) in the niclosamide-resistant cells than in the niclosamide-sensitive cells, suggesting that deficient autophagy induction by niclosamide compromises the effect of niclosamide on Wnt signaling.	Niclosamide	124-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	96-101	
29257330-7	2018	The expression levels of cisplatin-resistant-associated molecules (lung resistance-related protein and c-myc) following niclosamide treatment in A549/DDP cells were evaluated by western blot analysis.	Niclosamide	120-131	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	103-108	
29257330-9	2018	Furthermore, niclosamide decreased the expression level of c-myc protein, which may influence DDP sensitivity of A549/DDP cells.	Niclosamide	13-24	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	59-64	
28529629-10	2017	Niclosamide caused a dose- and time-dependent reduction of beta-catenin and the key components [e.g., DVLs, phospho-GSK3beta (S9), c-Myc and Cyclin D1] in the canonical Wnt/beta-catenin pathway.	Niclosamide	0-11	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	131-136	
29843133-8	2018	Mechanistically, Niclosamide inhibits the expression of C-MYC and E2F1 while inducing the expression of PTEN in RCC cells.	Niclosamide	17-28	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	56-61	
26118906-10	2015	Analysis of niclosamide"s effect on 11 cancer-related signal pathway reporters reveals that three of them, the E2F1, AP1, and c-Myc-responsive reporters, are significantly inhibited.	Niclosamide	12-23	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	126-131