PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32010892-6 2019 Significantly decreased serum levels of inflammatory biomarkers including TNF-alpha, IL-1beta, and IL-6 were observed in rats treated with high-dose oral NCL or intramuscular injection of diclofenac sodium, compared with groups B and C. Histopathological examination revealed that a high dose of NCL significantly reduced the infiltration of inflammatory cells, synovial hyperplasia, and bone and cartilage destruction. Niclosamide 154-157 tumor necrosis factor Rattus norvegicus 74-83