PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35008910-0	2022	Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.	Niclosamide	0-11	transforming growth factor beta induced	Homo sapiens	88-93	
35008910-7	2022	The results indicated that niclosamide, at concentrations of up to 200 nM, inhibited the migration and invasion of human osteosarcoma U2OS and HOS cells and repressed the transforming growth factor beta-induced protein (TGFBI) expression of U2OS cells, without cytotoxicity.	Niclosamide	27-38	transforming growth factor beta induced	Homo sapiens	220-225	
35008910-9	2022	Moreover, niclosamide significantly decreased the phosphorylation of ERK1/2 in U2OS cells and the combination treatment of the MEK inhibitor (U0126) and niclosamide resulted in the intensive inhibition of the TGFBI expression and the migratory ability in U2OS cells.	Niclosamide	10-21	transforming growth factor beta induced	Homo sapiens	209-214	
35008910-9	2022	Moreover, niclosamide significantly decreased the phosphorylation of ERK1/2 in U2OS cells and the combination treatment of the MEK inhibitor (U0126) and niclosamide resulted in the intensive inhibition of the TGFBI expression and the migratory ability in U2OS cells.	Niclosamide	153-164	transforming growth factor beta induced	Homo sapiens	209-214	
35008910-10	2022	Therefore, TGFBI derived from osteosarcoma cells via the ERK pathway contributed to cellular migration and invasion and niclosamide inhibited these processes.	Niclosamide	120-131	transforming growth factor beta induced	Homo sapiens	11-16