PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30329025-4	2019	Niclosamide dose dependently reduced 12Z viability, reduced STAT3 and NF${\rm \small K}$B activity, and increased both cleaved caspase-3 and cleaved PARP.	Niclosamide	0-11	caspase 3	Homo sapiens	127-136	
29257330-8	2018	The results indicated that niclosamide in combination with DDP demonstrated a synergistic effect in A549/DDP cells and directly induced apoptosis, which may be associated with caspase-3 activation.	Niclosamide	27-38	caspase 3	Homo sapiens	176-185	
21871175-5	2011	Moreover, niclosamide led to apoptotic cell death by caspase-3 activation.	Niclosamide	10-21	caspase 3	Homo sapiens	53-62	
26703449-6	2016	The activation of mitochondrial pathway in niclosamide-treated RA FLS induced the cytochrome C, cleavage of caspase-9 and caspase-3.	Niclosamide	43-54	caspase 3	Homo sapiens	122-131	
34913075-13	2022	Furthermore, niclosamide upregulated protein expression of cleaved caspase-3 and LC3B, while downregulated those of Bcl-2 and p62, in a dose-dependent manner in both Jurkat and CCRF-CEM cells.	Niclosamide	13-24	caspase 3	Homo sapiens	67-76	
35460941-5	2022	The results showed, briefly, an exposure to niclosamide and quinacrine led to an increased apoptosis-related protein p53, cleaved caspase-3 and cleaved PARP and autophagy-related protein LC3B expression, and a decreased expression of autophagy-related protein p62, finally leading to cell apoptosis and autophage.	Niclosamide	44-55	caspase 3	Homo sapiens	130-139	
33476693-9	2021	Indeed, our data indicated that niclosamide hindered RSV infection via proapoptotic activity by a reduction of AKT prosurvival protein, activation of cleaved caspase-3 and PARP (poly ADP-ribose polymerase), and an early apoptosis induction.	Niclosamide	32-43	caspase 3	Homo sapiens	158-167