PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33961984-8	2021	niclosamide (5 and 10 mg/kg) significantly reduced liver enzymes levels, oxidative stress, inflammation and phosphorylated signal transducer and activator of transcription3 (p-STAT3).	Niclosamide	0-11	signal transducer and activator of transcription 3	Rattus norvegicus	123-172	
32795515-3	2020	We hypothesized that niclosamide, a STAT3 inhibitor, would reduce vascular remodeling in an established pulmonary arterial hypertension model, thus enhancing cardiac function.	Niclosamide	21-32	signal transducer and activator of transcription 3	Rattus norvegicus	36-41	
33961984-8	2021	niclosamide (5 and 10 mg/kg) significantly reduced liver enzymes levels, oxidative stress, inflammation and phosphorylated signal transducer and activator of transcription3 (p-STAT3).	Niclosamide	0-11	signal transducer and activator of transcription 3	Rattus norvegicus	176-181	
29486057-1	2018	BACKGROUND AND PURPOSE: The anti-helminthic drug niclosamide regulates multiple cellular signals including STAT3, AMP-activated protein kinase (AMPK), Akt, Wnt/beta-catenin and mitochondrial uncoupling which are involved in neointimal hyperplasia.	Niclosamide	49-60	signal transducer and activator of transcription 3	Rattus norvegicus	107-112	
29935261-6	2018	The typical types of chemical mitochondrial uncouplers, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), niclosamide, and BAM15, induced biphasic change of STAT3 activity in cardiomyocytes, activating STAT3 at low dose and inhibiting STAT3 at high dose, though the dose range of these drugs was distinct.	Niclosamide	117-128	signal transducer and activator of transcription 3	Rattus norvegicus	168-173	
29935261-6	2018	The typical types of chemical mitochondrial uncouplers, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), niclosamide, and BAM15, induced biphasic change of STAT3 activity in cardiomyocytes, activating STAT3 at low dose and inhibiting STAT3 at high dose, though the dose range of these drugs was distinct.	Niclosamide	117-128	signal transducer and activator of transcription 3	Rattus norvegicus	213-218	
29935261-6	2018	The typical types of chemical mitochondrial uncouplers, carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), niclosamide, and BAM15, induced biphasic change of STAT3 activity in cardiomyocytes, activating STAT3 at low dose and inhibiting STAT3 at high dose, though the dose range of these drugs was distinct.	Niclosamide	117-128	signal transducer and activator of transcription 3	Rattus norvegicus	213-218	
29486057-8	2018	Niclosamide treatment inhibited serum-induced (15% FBS) and PDGF-BB-induced STAT3 activation (increased protein levels of p-STAT3 at Tyr705 ) but activated AMPK, in A10 cells.	Niclosamide	0-11	signal transducer and activator of transcription 3	Rattus norvegicus	76-81	
29486057-8	2018	Niclosamide treatment inhibited serum-induced (15% FBS) and PDGF-BB-induced STAT3 activation (increased protein levels of p-STAT3 at Tyr705 ) but activated AMPK, in A10 cells.	Niclosamide	0-11	signal transducer and activator of transcription 3	Rattus norvegicus	124-129	
29486057-12	2018	CONCLUSIONS AND IMPLICATIONS: Niclosamide inhibited vascular smooth muscle cell proliferation and migration and attenuated neointimal hyperplasia in balloon-injured rat carotid arteries through a mechanism involving inhibition of STAT3.	Niclosamide	30-41	signal transducer and activator of transcription 3	Rattus norvegicus	230-235