PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21835258-0	2012	The COX-2 inhibitor Celecoxib enhances the sensitivity of KB/VCR oral cancer cell lines to Vincristine by down-regulating P-glycoprotein expression and function.	Vincristine	91-102	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-9	
24849444-4	2014	RESULTS: Compared with the negative and blank control groups, COX-2 siRNA transfection resulted in significant growth inhibition of KB/VCR cells exposed to vincristine (P<0.01), down-regulated the expressions of COX-2 and MDR-1 mRNAs, and obviously increased Rho-123 accumulation in KB/VCR cells.	Vincristine	156-167	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	62-67	
24849444-5	2014	CONCLUSION: COX-2 gene silencing can enhance the chemosensitivity of KB/VCR cells to vincristine, the mechanism of which may involve down-regulated MDR-1 gene expression and inhibition of P-glycoprotein activity.	Vincristine	85-96	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	12-17