PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17331166-1 2007 BACKGROUND: Recently, ME3738, a derivative of soyasapogenol B, was developed as an inducer of interleukin (IL)-6. ME3738 22-28 interleukin 6 Rattus norvegicus 94-112 17331166-2 2007 It has been demonstrated that ME3738 is stimulate to produce IL-6 and that it protects against concanavalin A-induced liver failure. ME3738 30-36 interleukin 6 Rattus norvegicus 61-65 17331166-13 2007 Immunohistochemical staining of IL-6 was observed in perivenular hepatocytes of all rats, with its intensity becoming stronger in the order of controls, controls containing ME3738, ethanol, and ethanol-containing ME3738-fed rats. ME3738 173-179 interleukin 6 Rattus norvegicus 32-36 17331166-13 2007 Immunohistochemical staining of IL-6 was observed in perivenular hepatocytes of all rats, with its intensity becoming stronger in the order of controls, controls containing ME3738, ethanol, and ethanol-containing ME3738-fed rats. ME3738 213-219 interleukin 6 Rattus norvegicus 32-36 17331166-18 2007 CONCLUSIONS: Oral administration of ME3738, inducer of IL-6 may prevent the development of fatty liver caused by chronic ethanol consumption. ME3738 36-42 interleukin 6 Rattus norvegicus 55-59