PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33499800-5	2021	METHODS AND RESULTS: Activation of the transcription factors NF-kappaB and AP-1 was measured in IL-1beta-treated primary astrocytes incubated with various concentrations of DHA.	Dihydroalprenolol	173-176	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	75-79	
33499800-7	2021	DHA treatment inhibited translocation of p65NF-kappaB to the nucleus, significantly lowered p65NF-kappaB protein level and fluorescence of p65NF-kappaB in the nucleus, reduced dose-dependently IkappaB protein phosphorylation, and the binding of the AP-1 transcription factor members (c-Jun/c-Fos) to the specific TPA-response element (TRE) of DNA.	Dihydroalprenolol	0-3	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	284-289	
16335792-3	2005	In HL-60 cells treated with 50 microM 18:1/DHA-PE and 200 microM dbcAMP for 24 h, the expression level of c-jun mRNA and c-Jun protein were remarkably elevated compared to cells treated with dbcAMP alone.	Dihydroalprenolol	43-46	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	106-111	
16335792-3	2005	In HL-60 cells treated with 50 microM 18:1/DHA-PE and 200 microM dbcAMP for 24 h, the expression level of c-jun mRNA and c-Jun protein were remarkably elevated compared to cells treated with dbcAMP alone.	Dihydroalprenolol	43-46	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	121-126	
16335792-7	2005	Thus, 18:1/DHA-PE might enhance dbcAMP-induced HL-60 cell differentiation and growth inhibition by regulation of c-jun and c-myc mRNA and their products.	Dihydroalprenolol	11-14	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	113-118