PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25767823-0	2014	The PBDE metabolite 6-OH-BDE 47 affects melanin pigmentation and THRbeta MRNA expression in the eye of zebrafish embryos.	6-oh-bde	20-28	thyroid hormone receptor beta	Danio rerio	65-72	
25767823-6	2014	Interestingly, exposure to the native thyroid hormone, triiodothyronine (T3) also led to similar responses: decreased THRbeta mRNA expression, decreased melanin pigmentation and increased apoptosis, suggesting that 6-OH-BDE 47 may be acting as a T3 mimic.	6-oh-bde	215-223	thyroid hormone receptor beta	Danio rerio	118-125	
25767823-8	2014	Knock down of THRbeta led to decreases in melanin pigmentation and increases in apoptotic cells in the eye of zebrafish embryos, similar to exposure to T3 and 6-OH-BDE 47, but THRbeta mRNA overexpression rescued these effects.	6-oh-bde	159-167	thyroid hormone receptor beta	Danio rerio	14-21	
25767823-10	2014	This study suggests that 6-OH-BDE 47 disrupts the activity of THRbeta in early life stages of zebrafish, and warrants further studies on effects in developing humans.	6-oh-bde	25-33	thyroid hormone receptor beta	Danio rerio	62-69