PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12149127-1	2002	Sphingosine 1-phosphate (S1P), a metabolite of sphingomyelin degradation, stimulates interleukin-8 (IL-8) secretion in human bronchial epithelial (Beas-2B) cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	85-98	
19285497-0	2009	Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	60-64	
17306937-0	2007	The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells.	sphingosine 1-phosphate	12-35	C-X-C motif chemokine ligand 8	Homo sapiens	66-70	
17306937-3	2007	Although sphingolipids such as ceramide and sphingosine 1-phosphate (S1-P) have been shown to serve as signaling molecules in the TNF-alpha inflammatory response, their role in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells is not known.	sphingosine 1-phosphate	44-67	C-X-C motif chemokine ligand 8	Homo sapiens	204-208	
17306937-3	2007	Although sphingolipids such as ceramide and sphingosine 1-phosphate (S1-P) have been shown to serve as signaling molecules in the TNF-alpha inflammatory response, their role in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells is not known.	sphingosine 1-phosphate	69-73	C-X-C motif chemokine ligand 8	Homo sapiens	204-208	
12149127-1	2002	Sphingosine 1-phosphate (S1P), a metabolite of sphingomyelin degradation, stimulates interleukin-8 (IL-8) secretion in human bronchial epithelial (Beas-2B) cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	100-104	
12039947-0	2002	Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells.	sphingosine 1-phosphate	30-53	C-X-C motif chemokine ligand 8	Homo sapiens	64-77	
12162465-7	2002	In airway epithelial cells, sphingosine-1-phosphate and PA-induced IL-8 secretion and ERKI/2 phosphorylation is regulated by PA.	sphingosine 1-phosphate	28-51	C-X-C motif chemokine ligand 8	Homo sapiens	67-71	
26321412-0	2015	Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	34-38	
24647471-0	2014	Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	59-63	
25275309-3	2014	Exposure of cells to sphingosine 1-phosphate induced pro-inflammatory responses characterized by interleukin-6, interleukin-8, and cyclooxygenase-2 up-regulations, as observed by ELISA and Western blot.	sphingosine 1-phosphate	21-44	C-X-C motif chemokine ligand 8	Homo sapiens	112-125	
24743449-0	2014	Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	38-51	
24743449-0	2014	Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	53-57	
24743449-0	2014	Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.	sphingosine 1-phosphate	25-28	C-X-C motif chemokine ligand 8	Homo sapiens	38-51	
24743449-0	2014	Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.	sphingosine 1-phosphate	25-28	C-X-C motif chemokine ligand 8	Homo sapiens	53-57	
24743449-2	2014	Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil chemoattractant Interleukin-8 (IL-8) by epithelial cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	162-175	
24743449-2	2014	Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil chemoattractant Interleukin-8 (IL-8) by epithelial cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	177-181	
24743449-2	2014	Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil chemoattractant Interleukin-8 (IL-8) by epithelial cells.	sphingosine 1-phosphate	25-28	C-X-C motif chemokine ligand 8	Homo sapiens	162-175	
24743449-2	2014	Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil chemoattractant Interleukin-8 (IL-8) by epithelial cells.	sphingosine 1-phosphate	25-28	C-X-C motif chemokine ligand 8	Homo sapiens	177-181	
23345392-0	2013	Sphingosine-1-phosphate suppresses TLR-induced CXCL8 secretion from human T cells.	sphingosine 1-phosphate	0-23	C-X-C motif chemokine ligand 8	Homo sapiens	47-52	
24586752-4	2014	We found that the ceramide metabolite sphingosine-1-phosphate (S1P) stimulated the production of inflammatory mediators such as TNF-alpha and IL-8 from three-dimensionally cultured human primary keratinocytes (termed "3D keratinocytes"), which form a stratum corneum.	sphingosine 1-phosphate	38-61	C-X-C motif chemokine ligand 8	Homo sapiens	142-146	
24586752-4	2014	We found that the ceramide metabolite sphingosine-1-phosphate (S1P) stimulated the production of inflammatory mediators such as TNF-alpha and IL-8 from three-dimensionally cultured human primary keratinocytes (termed "3D keratinocytes"), which form a stratum corneum.	sphingosine 1-phosphate	63-66	C-X-C motif chemokine ligand 8	Homo sapiens	142-146