PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25446581-6 2015 The guaiane sesquiterpene is lacking the methylene-gamma-lactone function that is typically involved in the inhibiting properties of sesquiterpenes on NF-kappaB, a pivotal transcription factor in inflammatory processes. Sesquiterpenes 133-147 nuclear factor kappa B subunit 1 Homo sapiens 151-160 25446581-6 2015 The guaiane sesquiterpene is lacking the methylene-gamma-lactone function that is typically involved in the inhibiting properties of sesquiterpenes on NF-kappaB, a pivotal transcription factor in inflammatory processes. Sesquiterpenes 12-25 nuclear factor kappa B subunit 1 Homo sapiens 151-160 17149609-3 2007 The aim of this study was to investigate the effects of sesquiterpenes isolated from Asteraceae, namely melampolides (enhydrin, tetraludin A) and repandolides (repandins A, B, D and E) on the activation of NF-kappaB, cell growth of cancer cells, cell cycle progression and apoptosis. Sesquiterpenes 56-70 nuclear factor kappa B subunit 1 Homo sapiens 206-215 10704251-3 2000 Because activation of NF-kappaB is involved in the regulation of the chemokine interleukin 8 (IL-8), we hypothesized that the sesquiterpene lactones, isohelenin and parthenolide, would inhibit IL-8 gene expression in cultured human respiratory epithelium. Sesquiterpenes 126-139 nuclear factor kappa B subunit 1 Homo sapiens 22-31 34179914-0 2021 Bisabolane-type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-kappaB/MAPK and RIG-1/STAT1/2 signaling pathways. Sesquiterpenes 16-32 nuclear factor kappa B subunit 1 Homo sapiens 117-126 34179914-8 2021 These findings indicate that bisabolane-type sesquiterpenoids of C. longa could inhibit the expression of inflammatory cytokines induced by the virus and regulate the activity of NF-kappaB/MAPK and RIG-1/STAT-1/2 signaling pathways in vitro. Sesquiterpenes 45-61 nuclear factor kappa B subunit 1 Homo sapiens 179-188