PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21367956-9 2011 Taken together, these findings suggest that upregulation of HO-1 expression by zerumbone is mediated through activation of Nrf2 signaling, which provides a mechanistic basis for the chemopreventive effects of this sesquiterpene on mouse skin carcinogenesis. Sesquiterpenes 214-227 heme oxygenase 1 Mus musculus 60-64 21843620-7 2011 Among 12 compounds isolated from ECR, mostly sesquiterpenes induced stronger HO-1 expression than monoterpenes in macrophage cells. Sesquiterpenes 45-59 heme oxygenase 1 Mus musculus 77-81 21843620-11 2011 CONCLUSIONS: Taken together, we concluded that possible anti-inflammatory mechanism of ECR is, at least, due to HO-1 induction, in which sesquiterpenes such as nootkatone and valencene play a crucial role. Sesquiterpenes 137-151 heme oxygenase 1 Mus musculus 112-116 26950613-2 2016 In the present study, we investigated the anti-inflammatory signaling pathway via the upregulation of heme oxygenase-1 (HO-1) in response to tussilagonone (TGN), a sesquiterpene compound isolated from T. farfara. Sesquiterpenes 164-177 heme oxygenase 1 Mus musculus 102-118 26950613-2 2016 In the present study, we investigated the anti-inflammatory signaling pathway via the upregulation of heme oxygenase-1 (HO-1) in response to tussilagonone (TGN), a sesquiterpene compound isolated from T. farfara. Sesquiterpenes 164-177 heme oxygenase 1 Mus musculus 120-124