PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24407487-4 2014 The (GT)n and (TA)n dinucleotide variations in heme oxygenase 1 (HMOX1) and bilirubin UDP-glucuronosyl transferase (UGT1A1) gene promoters were determined by fragment analysis. Dinucleoside Phosphates 20-32 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 116-122 30583998-9 2019 CONCLUSION: Dinucleotide polymorphism in the promoter region of the UGT1A1 gene is not associated with a specific colonic phenotype in patients with sporadic colorectal cancer. Dinucleoside Phosphates 12-24 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 68-74 21911884-3 2011 The (GT)n and (TA)n dinucleotide variations in HMOX1 and UGT1A1 gene promoters, respectively, were determined by fragment analysis in all subjects. Dinucleoside Phosphates 20-32 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 57-63 17196409-2 2007 The causative mutation in Caucasians is almost exclusively a TA dinucleotide insertion in the TATA box of the UGT1A1 promoter. Dinucleoside Phosphates 64-76 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 110-116 20096102-3 2010 Interestingly, one of these CpG dinucleotides (CpG -4) is found close to a HNF1 response element (HRE), known to be involved in activation of UGT1A1 gene expression, and within an upstream stimulating factor (USF) binding site. Dinucleoside Phosphates 32-45 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 142-148 14744740-2 2004 The UGT1A1*28 allelic variant contains an additional (TA) dinucleotide repeat in the "TATAA" box [(TA)(6)>(TA)(7)] of the UGT1A1 promoter that has been linked to decreased expression of the UGT1A1 gene and decreased bilirubin conjugation, leading to the relatively nondebilitating condition known as Gilbert"s syndrome. Dinucleoside Phosphates 58-70 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 4-10 15469406-4 2004 A common dinucleotide repeat polymorphism in the UGT1A1 promoter region (UGT1A1*28) has been correlated with severe toxicity in cancer patients receiving irinotecan-containing therapy. Dinucleoside Phosphates 9-21 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 49-55 15469406-4 2004 A common dinucleotide repeat polymorphism in the UGT1A1 promoter region (UGT1A1*28) has been correlated with severe toxicity in cancer patients receiving irinotecan-containing therapy. Dinucleoside Phosphates 9-21 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 73-79 15099818-1 2004 A dinucleotide repeat polymorphism (5-, 6-, 7-, or 8-TA units) has been identified within the promoter region of UDP-glucuronosyltransferase 1A1 (UGT1A1) gene. Dinucleoside Phosphates 2-14 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 113-144 15099818-1 2004 A dinucleotide repeat polymorphism (5-, 6-, 7-, or 8-TA units) has been identified within the promoter region of UDP-glucuronosyltransferase 1A1 (UGT1A1) gene. Dinucleoside Phosphates 2-14 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 146-152 14744740-2 2004 The UGT1A1*28 allelic variant contains an additional (TA) dinucleotide repeat in the "TATAA" box [(TA)(6)>(TA)(7)] of the UGT1A1 promoter that has been linked to decreased expression of the UGT1A1 gene and decreased bilirubin conjugation, leading to the relatively nondebilitating condition known as Gilbert"s syndrome. Dinucleoside Phosphates 58-70 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 125-131 14744740-2 2004 The UGT1A1*28 allelic variant contains an additional (TA) dinucleotide repeat in the "TATAA" box [(TA)(6)>(TA)(7)] of the UGT1A1 promoter that has been linked to decreased expression of the UGT1A1 gene and decreased bilirubin conjugation, leading to the relatively nondebilitating condition known as Gilbert"s syndrome. Dinucleoside Phosphates 58-70 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 125-131 12850481-2 2003 The molecular basis of this syndrome usually concerns an additional dinucleotide insertion (TA) in the A(TA)(n)TAA configuration residing in the promoter region of the UGT1 A1 gene. Dinucleoside Phosphates 68-80 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 168-175 11174102-2 2001 Recently, the genetic basis of GS has been identified in caucasian populations : it is related to the insertion of a dinucleotide (TA) in the promoter region of the UGT1A1 gene. Dinucleoside Phosphates 117-129 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 165-171 10530490-2 1999 Recent molecular genetic studies have determined that the clinical phenotype can be described by a dinucleotide polymorphism in the TATA box promoter of the bilirubin uridine diphosphate-glucuronosyltransferase (UGT-1A1) gene, most frequently (TA)7TAA, affecting up to 36% of Africans, but only 3% of Asians. Dinucleoside Phosphates 99-111 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 212-219 35527687-2 2022 The expression of UGT1A1 is relatively managed by a polymorphic dinucleotide repeat inside the promoter TATA box consisting of 5-8 copies of a TA repeat. Dinucleoside Phosphates 64-76 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 18-24