PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21504622-0	2011	Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells.	isochaihulactone	50-66	mitogen-activated protein kinase 8	Homo sapiens	24-27	
21504622-11	2011	Isochaihulactone induced phosphorylation of c-Jun-N-terminal kinase (JNK), and JNK inhibitor partially reduced isochaihulactone-induced cell death.	isochaihulactone	0-16	mitogen-activated protein kinase 8	Homo sapiens	44-67	
21504622-11	2011	Isochaihulactone induced phosphorylation of c-Jun-N-terminal kinase (JNK), and JNK inhibitor partially reduced isochaihulactone-induced cell death.	isochaihulactone	0-16	mitogen-activated protein kinase 8	Homo sapiens	69-72	
21504622-11	2011	Isochaihulactone induced phosphorylation of c-Jun-N-terminal kinase (JNK), and JNK inhibitor partially reduced isochaihulactone-induced cell death.	isochaihulactone	111-127	mitogen-activated protein kinase 8	Homo sapiens	44-67	
21504622-11	2011	Isochaihulactone induced phosphorylation of c-Jun-N-terminal kinase (JNK), and JNK inhibitor partially reduced isochaihulactone-induced cell death.	isochaihulactone	111-127	mitogen-activated protein kinase 8	Homo sapiens	69-72	
21504622-11	2011	Isochaihulactone induced phosphorylation of c-Jun-N-terminal kinase (JNK), and JNK inhibitor partially reduced isochaihulactone-induced cell death.	isochaihulactone	111-127	mitogen-activated protein kinase 8	Homo sapiens	79-82	
21504622-14	2011	CONCLUSIONS: Isochaihulactone apparently induces G2/M cell cycle arrest via downregulation of cyclin B1 and cdc2, and induces cellular death by upregulation of NAG-1 via JNK activation in LNCaP cells.	isochaihulactone	13-29	mitogen-activated protein kinase 8	Homo sapiens	170-173