PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9271379-7	1997	In contrast, exposure to the alkylating agent methyl methanesulfonate results in similar increases of p53 and p21(WAF1/CIP1) mRNA in both cell types.	Methyl Methanesulfonate	46-69	cyclin dependent kinase inhibitor 1A	Homo sapiens	110-113	
10749849-2	2000	We show that the gene encoding the gut-enriched Kruppel-like factor (GKLF, KLF4) is concurrently induced with p21(WAF1/Cip1) during serum deprivation and DNA damage elicited by methyl methanesulfonate.	Methyl Methanesulfonate	177-200	cyclin dependent kinase inhibitor 1A	Homo sapiens	110-113	
10749849-2	2000	We show that the gene encoding the gut-enriched Kruppel-like factor (GKLF, KLF4) is concurrently induced with p21(WAF1/Cip1) during serum deprivation and DNA damage elicited by methyl methanesulfonate.	Methyl Methanesulfonate	177-200	cyclin dependent kinase inhibitor 1A	Homo sapiens	114-118	
10749849-2	2000	We show that the gene encoding the gut-enriched Kruppel-like factor (GKLF, KLF4) is concurrently induced with p21(WAF1/Cip1) during serum deprivation and DNA damage elicited by methyl methanesulfonate.	Methyl Methanesulfonate	177-200	cyclin dependent kinase inhibitor 1A	Homo sapiens	119-123	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	117-120	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	121-125	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	126-130	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	190-193	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	194-198	
10749849-4	2000	Moreover, during the first 30 min of methyl methanesulfonate treatment, the rise in Gklf mRNA level precedes that in p21(WAF1/Cip1), suggesting that GKLF may be involved in the induction of p21(WAF1/Cip1).	Methyl Methanesulfonate	37-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	199-203	
25883782-6	2015	The utility of the approach was demonstrated by the analysis of the effects of the drug (methyl methanesulfonate, MMS) on the induction of the cyclin-dependent kinase inhibitor 1a (CDKN1A) in single human cancer cells (MCF-7), demonstrating the potential of our approach for efficient, integrated single-cell RT-qPCR for gene expression analysis.	Methyl Methanesulfonate	89-112	cyclin dependent kinase inhibitor 1A	Homo sapiens	143-179	
25883782-6	2015	The utility of the approach was demonstrated by the analysis of the effects of the drug (methyl methanesulfonate, MMS) on the induction of the cyclin-dependent kinase inhibitor 1a (CDKN1A) in single human cancer cells (MCF-7), demonstrating the potential of our approach for efficient, integrated single-cell RT-qPCR for gene expression analysis.	Methyl Methanesulfonate	89-112	cyclin dependent kinase inhibitor 1A	Homo sapiens	181-187	
18458079-3	2008	We have recently found that the p21-dependent checkpoint can be activated and induce a prolonged arrest if S phase cells are damaged with a base-modifying agent, such as methyl methanesulfonate (MMS) and cisplatin.	Methyl Methanesulfonate	170-193	cyclin dependent kinase inhibitor 1A	Homo sapiens	32-35	
18458079-3	2008	We have recently found that the p21-dependent checkpoint can be activated and induce a prolonged arrest if S phase cells are damaged with a base-modifying agent, such as methyl methanesulfonate (MMS) and cisplatin.	Methyl Methanesulfonate	195-198	cyclin dependent kinase inhibitor 1A	Homo sapiens	32-35	
11890931-6	2002	Nuclear extracts from MMS-treated HCT-116 cells had higher p21WAF1/Cip1 (p21) promoter DNA-binding activity in vitro opposed to untreated cells.	Methyl Methanesulfonate	22-25	cyclin dependent kinase inhibitor 1A	Homo sapiens	59-71	
11890931-6	2002	Nuclear extracts from MMS-treated HCT-116 cells had higher p21WAF1/Cip1 (p21) promoter DNA-binding activity in vitro opposed to untreated cells.	Methyl Methanesulfonate	22-25	cyclin dependent kinase inhibitor 1A	Homo sapiens	59-62	
9271379-7	1997	In contrast, exposure to the alkylating agent methyl methanesulfonate results in similar increases of p53 and p21(WAF1/CIP1) mRNA in both cell types.	Methyl Methanesulfonate	46-69	cyclin dependent kinase inhibitor 1A	Homo sapiens	114-118	
9271379-7	1997	In contrast, exposure to the alkylating agent methyl methanesulfonate results in similar increases of p53 and p21(WAF1/CIP1) mRNA in both cell types.	Methyl Methanesulfonate	46-69	cyclin dependent kinase inhibitor 1A	Homo sapiens	119-123	
8900110-7	1996	Cells lacking the c-abl gene also responded to ara-C and MMS with increases in p53 levels and induction of p21.	Methyl Methanesulfonate	57-60	cyclin dependent kinase inhibitor 1A	Homo sapiens	107-110	
7478567-4	1995	In contrast, the increase in p53 protein, WAF1/CIP1(p21) and GADD45 mRNA expression following exposure to the alkylating agent methylmethane sulphonate (25 and 100 micrograms ml-1) was similar in both cell types.	Methyl Methanesulfonate	127-151	cyclin dependent kinase inhibitor 1A	Homo sapiens	52-55