PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10426999-5	1999	Ectopic expression of wild-type, but not mutated, BRCA1 in these cells rendered them less sensitive to the DNA damage agent, methyl methanesulfonate.	Methyl Methanesulfonate	125-148	BRCA1 DNA repair associated	Homo sapiens	50-55	
23826138-4	2013	Here, we examined a BRCA1 role in BER, first in relation to alkylating agent (MMS) treatment of cells and the BER enzyme DNA polymerase beta (pol beta).	Methyl Methanesulfonate	78-81	BRCA1 DNA repair associated	Homo sapiens	20-25	
27484786-0	2016	Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.	Methyl Methanesulfonate	63-66	BRCA1 DNA repair associated	Homo sapiens	29-34	
27484786-8	2016	We propose a model where BRCA1 cancer variants interact with the DNA double strand break repair pathways producing DNA recombination intermediates, that maybe less repairable and decrease MMS-induced recombination and survival.	Methyl Methanesulfonate	188-191	BRCA1 DNA repair associated	Homo sapiens	25-30	
21103343-5	2010	We established that, unlike ionizing radiation, either UVC or methylmethanesulfonate (MMS) (generating bulky DNA adducts or alkylated bases respectively) induces a transient downregulation of BRCA1 protein which is neither prevented nor enhanced by inhibition of PIKKs.	Methyl Methanesulfonate	62-84	BRCA1 DNA repair associated	Homo sapiens	192-197	
21103343-5	2010	We established that, unlike ionizing radiation, either UVC or methylmethanesulfonate (MMS) (generating bulky DNA adducts or alkylated bases respectively) induces a transient downregulation of BRCA1 protein which is neither prevented nor enhanced by inhibition of PIKKs.	Methyl Methanesulfonate	86-89	BRCA1 DNA repair associated	Homo sapiens	192-197	
18197258-9	2008	Finally, BRCA1, SPT5 and hyperphosphorylated RPB1 form a complex that was rapidly degraded following MMS treatment in wild type but not BRCA1 mutant breast cells.	Methyl Methanesulfonate	101-104	BRCA1 DNA repair associated	Homo sapiens	9-14