PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2685560-2	1989	Induction of the RNR2 transcript by at least one of these agents, methyl methanesulfonate, did not require protein synthesis.	Methyl Methanesulfonate	66-89	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	17-21	
16199065-6	2006	Reintroduction of FBP1 in the knockout restored the wild-type phenotype while overexpression increased MMS sensitivity of wild-type, shortened life span and increased induction of RNR2 after treatment with MMS.	Methyl Methanesulfonate	206-209	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	180-184	
16275785-6	2005	We show, however, that the HU sensitivity of ccr4-not mutant strains correlated very well with a defect in accumulation of RNR2, RNR3 and RNR4 mRNA after HU or methyl-methane sulfonate (MMS) treatment.	Methyl Methanesulfonate	160-184	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	123-127	
12172964-4	2002	RAD54 and RNR2 reporter activity in response to the DNA damaging agent, methyl methanesulphonate, was measured in ddc1-Delta, rad9-Delta, ddc1-Delta/rad9-Delta, dun1-Delta, crt1-Delta and mbp1-Delta mutants and was compared with that of the wild type.	Methyl Methanesulfonate	72-96	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	10-14	
17140446-8	2006	All of the genes (DUN1, RNR2, RNR4, and HUG1) are involved in the Mec1p kinase pathway known to respond to MMS, presumably due to stalled DNA replication forks.	Methyl Methanesulfonate	107-110	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	24-28	
2513480-4	1989	beta-Galactosidase activity in yeast strains containing the RNR2-lacZ fusion was inducible in response to DNA-damaging agents (UV light, 4-nitroquinoline-1-oxide [4-NQO], and methyl methanesulfonate [MMS]) and agents that block DNA replication (hydroxyurea [HU] and methotrexate) but not heat shock.	Methyl Methanesulfonate	175-198	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	60-64	
2513480-4	1989	beta-Galactosidase activity in yeast strains containing the RNR2-lacZ fusion was inducible in response to DNA-damaging agents (UV light, 4-nitroquinoline-1-oxide [4-NQO], and methyl methanesulfonate [MMS]) and agents that block DNA replication (hydroxyurea [HU] and methotrexate) but not heat shock.	Methyl Methanesulfonate	200-203	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	60-64	
2513480-7	1989	A mutation, rnr2-314, was found to confer hypersensitivity to HU and increased sensitivity to MMS.	Methyl Methanesulfonate	94-97	ribonucleotide-diphosphate reductase subunit RNR2	Saccharomyces cerevisiae S288C	12-16