PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19451401-0 2009 Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers. luciferin-isopropyl acetal 14-40 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 46-52 19451401-1 2009 This study represents the first report on the characterization of luciferin-isopropyl acetal (LIPA) as a CYP3A4 substrate in human hepatocytes. luciferin-isopropyl acetal 66-92 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 105-111 19451401-1 2009 This study represents the first report on the characterization of luciferin-isopropyl acetal (LIPA) as a CYP3A4 substrate in human hepatocytes. luciferin-isopropyl acetal 94-98 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 105-111 19451401-8 2009 Although the selectivity toward CYP3A4 needs to be definitively evaluated using cDNA-expressed P450 isoforms, the results suggest that LIPA is a suitable substrate to be used with human hepatocytes for the evaluation of CYP3A4 activities. luciferin-isopropyl acetal 135-139 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 220-226