PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17638882-6	2007	When the effects of TNF-alpha and iNOS were neutralized through the use of neutralizing antibody and N(G)-methyl-L-arginine, respectively, the enhanced cytotoxicity of TbetaRIIDN-RAW cells was partially reversed.	Nitroarginine	101-123	nitric oxide synthase 2, inducible	Mus musculus	34-38	
19673702-6	2010	Induction of iNOS expression in RAW264.7 cells with LPS (lipopolysaccharide; 1 microg/ml) causes a significant increase in PMA-induced chemiluminescence, which could be enhanced by the NOS substrate, L-arginine, and could be abolished by the NOS inhibitor, L-NNA (NG-nitro-L-arginine).	Nitroarginine	257-262	nitric oxide synthase 2, inducible	Mus musculus	13-17	
19673702-6	2010	Induction of iNOS expression in RAW264.7 cells with LPS (lipopolysaccharide; 1 microg/ml) causes a significant increase in PMA-induced chemiluminescence, which could be enhanced by the NOS substrate, L-arginine, and could be abolished by the NOS inhibitor, L-NNA (NG-nitro-L-arginine).	Nitroarginine	264-283	nitric oxide synthase 2, inducible	Mus musculus	13-17	
21043515-2	2010	Aiming at the design of innovative (99m)Tc(I) complexes for targeting inducible NOS (iNOS) in vivo by SPECT imaging, herein we describe a set of novel (99m)Tc(CO)3 complexes (2-5) and the corresponding rhenium surrogates (2a-5a) containing the NOS inhibitor N(omega)-nitro-l-arginine.	Nitroarginine	258-283	nitric oxide synthase 2, inducible	Mus musculus	85-89	
20637185-7	2010	Of note, some commercially available inhibitors for iNOS and/or COX-2, such as ibuprofen, dextromethorphan, and N(G)-methyl-l-arginine (l-NMA), show negligible effects on microglial Abeta phagocytosis.	Nitroarginine	112-134	nitric oxide synthase 2, inducible	Mus musculus	52-56	
17569362-7	2006	(3) N.-Nitro-L-arginine (L-NNA) significantly decreased the content of iNOS, NO and SOD in all above tissues and serum, and also decreased the content of cNOS in lung and kidney tissues and serum.	Nitroarginine	4-23	nitric oxide synthase 2, inducible	Mus musculus	71-75	
17569362-7	2006	(3) N.-Nitro-L-arginine (L-NNA) significantly decreased the content of iNOS, NO and SOD in all above tissues and serum, and also decreased the content of cNOS in lung and kidney tissues and serum.	Nitroarginine	25-30	nitric oxide synthase 2, inducible	Mus musculus	71-75	
17569362-12	2006	L-NNA, non-selective inhibitor of NOS, aggravates damage of tissues and increases mortality, though it can reduce the increase of iNOS and NO induced by lipopolysaccharide.	Nitroarginine	0-5	nitric oxide synthase 2, inducible	Mus musculus	130-134	
11257143-7	2001	Inhibition of NOS II by N(G)-methyl-l-arginine (LNMMA) restores the killing obtained in the presence of interferon (IFN)-gamma plus lipolysaccharide (LPS), whereas the nitric oxide scavenger 2-(4-carboxyphenyl)-4,4,5,5,-tetramethylimidazoline-3-oxide-1-oxyl (carboxy-PTIO) was without effect.	Nitroarginine	24-46	nitric oxide synthase 2, inducible	Mus musculus	14-20	
11331078-7	2001	Furthermore, N-nitro-L-arginine (NLA) and N-nitro-L-arginine methyl ester (L-NAME) pretreatment enhanced LPS-induced iNOS (but not COX-2) protein expression, which was inhibited by these three polyphenolic compounds.	Nitroarginine	13-31	nitric oxide synthase 2, inducible	Mus musculus	117-121	
11331078-7	2001	Furthermore, N-nitro-L-arginine (NLA) and N-nitro-L-arginine methyl ester (L-NAME) pretreatment enhanced LPS-induced iNOS (but not COX-2) protein expression, which was inhibited by these three polyphenolic compounds.	Nitroarginine	33-36	nitric oxide synthase 2, inducible	Mus musculus	117-121	
10590407-6	2000	The higher affinity ((3)H)L-NNA binding site colocalized with nNOS and the lower affinity site with iNOS.	Nitroarginine	26-31	nitric oxide synthase 2, inducible	Mus musculus	100-104	
11715524-10	1999	Furthermore, L-NNA decreased iNOS-specific protein expression in DPDPE-induced tolerance and naloxone-precipited withdrawal cells.	Nitroarginine	13-18	nitric oxide synthase 2, inducible	Mus musculus	29-33	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	359-378	nitric oxide synthase 2, inducible	Mus musculus	27-31	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	359-378	nitric oxide synthase 2, inducible	Mus musculus	38-42	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	359-378	nitric oxide synthase 2, inducible	Mus musculus	38-42	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	380-385	nitric oxide synthase 2, inducible	Mus musculus	27-31	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	380-385	nitric oxide synthase 2, inducible	Mus musculus	38-42	
12548860-3	1999	In the 2# clone expressing iNOS gene, iNOS catalytic activity in the cytosol fraction displayed to have an increasing trend, accompanying with the accumulation of NO2- content in the supernantant of cultured cells and the intracellular cGMP concentration, which suggested that NO-cGMP signal pathway was mediated by the expression of iNOS gene and blocked by NG-nitro-L-arginine (L-NNA) and methylene blue (MB).	Nitroarginine	380-385	nitric oxide synthase 2, inducible	Mus musculus	38-42	
12548860-4	1999	Activity of iNOS was concentration-dependently inhibited by NOS inhibitors such as L-NNA and aminoguanidine.	Nitroarginine	83-88	nitric oxide synthase 2, inducible	Mus musculus	12-16	
9091643-10	1997	This lysis was suppressed by the specific iNOS inhibitor N(G)-methyl-L-arginine.	Nitroarginine	57-79	nitric oxide synthase 2, inducible	Mus musculus	42-46