PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8728119-0	1996	Human cytochrome P450"s are pro-oxidants in iron/ascorbate-initiated microsomal lipid peroxidation.	Ascorbic Acid	49-58	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	6-21	
9279132-4	1997	Liver microsomal cytochrome P-450 level was found to be low in ascorbate deficient animals.	Ascorbic Acid	63-72	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	17-33	
9046019-0	1997	NADPH-initiated cytochrome P450-dependent free iron-independent microsomal lipid peroxidation: specific prevention by ascorbic acid.	Ascorbic Acid	118-131	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	16-31	
9046019-1	1997	In this paper we demonstrate that ascorbic acid specifically prevents NADPH-initiated cytochrome P450 (P450)-mediated microsomal lipid peroxidation in the absence of free iron.	Ascorbic Acid	34-47	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	86-101	
22900324-0	2003	Cytochrome P450-mediated oxidative damage of nuclear membrane proteins and its prevention by vitamin C.	Ascorbic Acid	93-102	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15	
8728119-1	1996	We have examined the effect of human cytochrome P450"s (1A1,1A2,3A4,2A6,2B6,2D6,2E1) on ascorbate/iron-induced lipid peroxidation.	Ascorbic Acid	88-97	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	37-52	
8728119-4	1996	It is therefore concluded that cytochrome P450"s play a significant role in ascorbate/iron peroxidation.	Ascorbic Acid	76-85	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	31-46	
1373902-6	1992	Western blot analysis of liver microsomes with antibodies to rat P-450IA2 (P-448-H), P-450IIB1 (P-450b) and human P-450IIIA4 (P-450NF) showed that ascorbic acid-deficiency resulted in a decrease in the amount of cytochrome P-450 immunochemically related to P-450IA2, but not the amounts of the forms of cytochrome P-450 cross-reactive with antibodies to P-450IIB1 and P-450IIIA4.	Ascorbic Acid	147-160	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	303-319	
8175769-4	1994	Ascorbate (AH2) specifically inhibits free metal ion-independent cyt P450-mediated protein oxidation and thereby prevents subsequent proteolytic degradation.	Ascorbic Acid	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-73	
3549274-7	1986	The high content of antioxidant compounds in the adrenal cortex, principally ascorbate, may serve to protect cytochrome P-450 enzymes from the damaging effects of oxygen radical species formed as a result of cytochrome P-450/pseudosubstrate interactions.	Ascorbic Acid	77-86	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	109-125	
3549274-7	1986	The high content of antioxidant compounds in the adrenal cortex, principally ascorbate, may serve to protect cytochrome P-450 enzymes from the damaging effects of oxygen radical species formed as a result of cytochrome P-450/pseudosubstrate interactions.	Ascorbic Acid	77-86	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	208-224	
3021236-2	1986	Vitamin C and tetramethyl-p-phenylene-diamine (TMPD) were used to increase oxygen consumption at the cytochrome a3 level, thereby decreasing its availability to cytochrome P-450.	Ascorbic Acid	0-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	161-177