PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34866234-8 2022 CONCLUSION: High dose ascorbic acid was associated with significantly reduced oxidative stress, reduced pro-inflammatory markers except IL-1beta, elevated anti-inflammatory marker, and elevated plasma VC levels. Ascorbic Acid 22-35 interleukin 1 alpha Homo sapiens 136-144 11120850-2 2000 We report in this study that vitamin C inhibits the activation of NF-kappaB by multiple stimuli, including IL-1 and TNF in the endothelial cell line ECV304 and in primary HUVECs. Ascorbic Acid 29-38 interleukin 1 alpha Homo sapiens 107-111 11120850-7 2000 Vitamin C was shown to block IL-1- and TNF-mediated degradation and phosphorylation of I-kappaBalpha (inhibitory protein that dissociates from NF-kappaB), due to inhibition of I-kappaB kinase (IKK) activation. Ascorbic Acid 0-9 interleukin 1 alpha Homo sapiens 29-33 9036929-0 1997 L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1alpha and IL-6 in cultured human keratinocytes in vitro. Ascorbic Acid 0-15 interleukin 1 alpha Homo sapiens 73-82 9036929-6 1997 L-Ascorbic acid was able to downregulate IL-1alpha mRNA expression in both UVA-irradiated and nonirradiated cells; however, IL-6 mRNA expression remained unaffected. Ascorbic Acid 0-15 interleukin 1 alpha Homo sapiens 41-50 34069836-0 2021 Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFkappaB/Caspase-1/IL-1beta Pathway. Ascorbic Acid 12-25 interleukin 1 alpha Homo sapiens 115-123 35623848-6 2022 The bioactive compounds including luteolin, epicatechin, epigallocatechin gallate, lycopene, quercetin, vitamin A, vitamin C and vitamin E in FBV significantly lowered TNF-alpha production, CCL2 production, IL-1beta production, and reactive oxygen species production. Ascorbic Acid 115-124 interleukin 1 alpha Homo sapiens 207-215 32228128-12 2020 CONCLUSION: The association between IL-1beta rs16944 genotype and CXCL10 levels was modified by the levels of ascorbic acid, alpha-tocopherol and vitamin D. Ascorbic Acid 110-123 interleukin 1 alpha Homo sapiens 36-44 33676147-0 2021 L-Threoascorbic acid treatment promotes S. aureus-infected primary human endothelial cells survival and function, as well as intracellular bacterial killing, and immunomodulates the release of IL-1beta and soluble ICAM-1. Ascorbic Acid 0-20 interleukin 1 alpha Homo sapiens 193-201