PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20223516-4 2010 When rec1-resilin is "pinned" to the substrate at IEP and subsequently exposed to an electrolyte solution adjusted to different pH, it switches from a compact globular conformation of the bio-macromolecule at the IEP to a coil conformation at pH between IEP to IED (IED = pKa value of tyrosine amino acid residue) and an extended coil conformation at pH > IED. tyrosine amino acid 285-304 RAD1 checkpoint DNA exonuclease Homo sapiens 5-9