PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32377738-0	2020	Coenzyme Q10 alleviates sevoflurane-induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons.	coenzyme Q10	0-12	apolipoprotein E	Mus musculus	90-106	
12885592-2	2003	Coenzyme Q(10) (CoQ(10)) in its reduced form, ubiquinol-10, effectively inhibits lipoprotein oxidation in vitro and in vivo; CoQ(10) supplements also inhibit atherosclerosis in apolipoprotein E gene knockout (apoE-/-) mice.	coenzyme Q10	16-19	apolipoprotein E	Mus musculus	177-193	
12885592-2	2003	Coenzyme Q(10) (CoQ(10)) in its reduced form, ubiquinol-10, effectively inhibits lipoprotein oxidation in vitro and in vivo; CoQ(10) supplements also inhibit atherosclerosis in apolipoprotein E gene knockout (apoE-/-) mice.	coenzyme Q10	16-19	apolipoprotein E	Mus musculus	209-217	
12885592-9	2003	Thus, like in apoE-/- mice, a high dose of supplemented CoQ(10) inhibits lipid oxidation in the artery wall of balloon-injured, hypercholesterolemic rabbits.	coenzyme Q10	56-59	apolipoprotein E	Mus musculus	14-18	
11304477-10	2001	Thus, in apoE-/- mice, VitE+CoQ(10) supplements are more antiatherogenic than CoQ(10) or VitE supplements alone and disease inhibition is associated with a decrease in aortic lipid hydroperoxides but not 7-ketocholesterol.	coenzyme Q10	28-35	apolipoprotein E	Mus musculus	9-13	
32792941-5	2020	Both in high fat diet (HFD) fed APOE -/- mice and in ox-LDL-treated HAECs, CoQ10 significantly decreased the levels of TG, TC and LDL-C and increased the levels of HDL-C, thus playing a role in regulating lipid homeostasis.	coenzyme Q10	75-80	apolipoprotein E	Mus musculus	32-36	
32377738-14	2020	CoQ10 improved energy replenishment and inhibited oxidative stress, which may lead to a decrease in ApoE and phosphorylated tau protein expression, thus mitigating the sevoflurane-induced neuroinflammation in mouse hippocampal neurons.	coenzyme Q10	0-5	apolipoprotein E	Mus musculus	100-104	
32473608-0	2020	Protective effects of Coenzyme Q10 against sevoflurane-induced cognitive impairment through regulating apolipoprotein E and phosphorylated Tau expression in young mice.	coenzyme Q10	22-34	apolipoprotein E	Mus musculus	103-119	
31755492-0	2020	Coenzyme Q10 attenuates platelet integrin alphaIIbbeta3 signaling and platelet hyper-reactivity in ApoE-deficient mice.	coenzyme Q10	0-12	apolipoprotein E	Mus musculus	99-103	
31755492-4	2020	We found that CoQ10 supplementation in ApoE-/- mice significantly alleviated formation of HFD-induced atherosclerotic lesions, and attenuated platelet hyper-aggregation and granule secretion, including CD62P, CD63 and CD40 ligand (CD40L) expression and platelet factor-4, beta-thromboglobulin and activation normal T cell expressed and secreted (CCL5) release.	coenzyme Q10	14-19	apolipoprotein E	Mus musculus	39-43	
32473608-12	2020	The results indicated that the injection of CoQ10 ahead of sevoflurane treatment could reversed the anesthesia induced energy deficiency, mitochondrial dysfunction, ApoE and its fragments expression, Abeta1-42 generation, Tau phosphorylation and cognitive impairment in young mice.	coenzyme Q10	44-49	apolipoprotein E	Mus musculus	165-169	
32473608-14	2020	CoQ10 could reduce ApoE expression by improving energy replenishment and mitochondrial functions, thereby alleviating sevoflurane-induced brain damage and cognitive impairment.	coenzyme Q10	0-5	apolipoprotein E	Mus musculus	19-23