PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34408002-7	2021	Mechanistically, PDSS1, but not a catalytically inactive mutant, positively regulated the cellular level of coenzyme Q10 (CoQ10) and intracellular calcium levels, thereby inducing CAMK2A phosphorylation, which is essential for STAT3 phosphorylation in the cytoplasm.	coenzyme Q10	108-120	decaprenyl diphosphate synthase subunit 1	Homo sapiens	17-22	
22231380-8	2012	The increasing number of molecular defects in enzymes of the CoQ(10) biosynthetic pathways (PDSS1, PDSS2, COQ2, COQ6, COQ9, CABC1/ADCK3) underlies the importance of these conditions.	coenzyme Q10	61-68	decaprenyl diphosphate synthase subunit 1	Homo sapiens	92-97	
33285023-5	2021	The visual system seems to be mainly involved when the first steps of CoQ10 synthesis are impaired (PDSS1, PDSS2, and COQ2 deficiency).	coenzyme Q10	70-75	decaprenyl diphosphate synthase subunit 1	Homo sapiens	100-105	
34408002-7	2021	Mechanistically, PDSS1, but not a catalytically inactive mutant, positively regulated the cellular level of coenzyme Q10 (CoQ10) and intracellular calcium levels, thereby inducing CAMK2A phosphorylation, which is essential for STAT3 phosphorylation in the cytoplasm.	coenzyme Q10	122-127	decaprenyl diphosphate synthase subunit 1	Homo sapiens	17-22	
34765390-1	2021	We report a detailed clinical examination in a patient with primary coenzyme Q10 deficiency caused by biallelic mutations in the PDSS1 gene who presented clinical features of mitochondrial encephalopathy associated with pulmonary hypertension, livedo reticularis and particularly, chronic distal phalangeal erythema.	coenzyme Q10	68-80	decaprenyl diphosphate synthase subunit 1	Homo sapiens	129-134	
34765390-6	2021	This is the first reported patient with PDSS1 mutations presenting with 3-methyl-glutaconic aciduria and distal phalangeal erythema, expanding the phenotype of primary coenzyme Q10 deficiency.	coenzyme Q10	168-180	decaprenyl diphosphate synthase subunit 1	Homo sapiens	40-45