PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33411248-6	2021	Intake of N-acetylcysteine, coenzyme Q10 and melatonin is accompanied by increased Nrf2 activity.	coenzyme Q10	28-40	NFE2 like bZIP transcription factor 2	Homo sapiens	83-87	
22057896-6	2013	Med and Med + CoQ diets induced lower Nrf2, p22(phox), p47(phox), SOD1, SOD2 and TrxR gene expression and higher cytoplasmic Nrf2 and Keap-1 protein levels compared to the SFA diet.	coenzyme Q10	14-17	NFE2 like bZIP transcription factor 2	Homo sapiens	38-42	
30991050-0	2019	The in vitro and in vivo depigmenting activity of Coenzyme Q10 through the down-regulation of alpha-MSH signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated skin keratinocytes.	coenzyme Q10	50-62	NFE2 like bZIP transcription factor 2	Homo sapiens	140-144	
30991050-8	2019	Notably, silencing of Nrf2 (siRNA transfection) significantly diminished CoQ10-mediated anti-melanogenic activity, as evidenced by impaired antioxidant HO-1 gene, uncontrolled ROS generation, and alpha-MSH production following UVA irradiation.	coenzyme Q10	73-78	NFE2 like bZIP transcription factor 2	Homo sapiens	22-26	
33743807-4	2021	In the present study, we determined that the CoQ10-induced anti-allergic effects were mediated by up-regulation of Nrf2.	coenzyme Q10	45-50	NFE2 like bZIP transcription factor 2	Homo sapiens	115-119	
33743807-12	2021	Importantly, Co-Q10 treatment increased Nrf2 expression and Nrf2 induced antioxidant genes, glutathione redox and inhibited inflammation, oxidative stress injury, Th2 cytokines production and attenuated allergic inflammatory responses.	coenzyme Q10	13-19	NFE2 like bZIP transcription factor 2	Homo sapiens	40-44	
33743807-12	2021	Importantly, Co-Q10 treatment increased Nrf2 expression and Nrf2 induced antioxidant genes, glutathione redox and inhibited inflammation, oxidative stress injury, Th2 cytokines production and attenuated allergic inflammatory responses.	coenzyme Q10	13-19	NFE2 like bZIP transcription factor 2	Homo sapiens	60-64	
33743807-14	2021	Co-Q10 increases the Nrf2 expression and the Nrf2 over-expression has strong effect in control of type2 cytokines, allergic mediators and inflammatory factors that lead to harnessing of allergy and asthma.	coenzyme Q10	0-6	NFE2 like bZIP transcription factor 2	Homo sapiens	21-25	
33743807-14	2021	Co-Q10 increases the Nrf2 expression and the Nrf2 over-expression has strong effect in control of type2 cytokines, allergic mediators and inflammatory factors that lead to harnessing of allergy and asthma.	coenzyme Q10	0-6	NFE2 like bZIP transcription factor 2	Homo sapiens	45-49	
24986061-5	2015	Following consumption of Med + CoQ, hippurate excretion was positively correlated with CoQ and beta-carotene plasma levels and inversely related to Nrf2, thioredoxin, superoxide dismutase 1, and gp91(phox) subunit of NADPH oxidase gene expression.	coenzyme Q10	31-34	NFE2 like bZIP transcription factor 2	Homo sapiens	148-152	
22057896-6	2013	Med and Med + CoQ diets induced lower Nrf2, p22(phox), p47(phox), SOD1, SOD2 and TrxR gene expression and higher cytoplasmic Nrf2 and Keap-1 protein levels compared to the SFA diet.	coenzyme Q10	14-17	NFE2 like bZIP transcription factor 2	Homo sapiens	125-129	
22057896-7	2013	Moreover, Med + CoQ diet produced lower postprandial Nrf2 gene expression and lower nuclear Nrf2 protein levels compared to the other diets and lower GPx1 gene expression than the SFA diet.	coenzyme Q10	16-19	NFE2 like bZIP transcription factor 2	Homo sapiens	53-57	
22057896-7	2013	Moreover, Med + CoQ diet produced lower postprandial Nrf2 gene expression and lower nuclear Nrf2 protein levels compared to the other diets and lower GPx1 gene expression than the SFA diet.	coenzyme Q10	16-19	NFE2 like bZIP transcription factor 2	Homo sapiens	92-96