PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18230681-2	2008	Last year, we reported the first mutations in CoQ(10) biosynthetic genes, COQ2, which encodes 4-parahydroxybenzoate: polyprenyl transferase; and PDSS2, which encodes subunit 2 of decaprenyl diphosphate synthase.	coenzyme Q10	46-53	decaprenyl diphosphate synthase subunit 2	Homo sapiens	145-150	
22231380-8	2012	The increasing number of molecular defects in enzymes of the CoQ(10) biosynthetic pathways (PDSS1, PDSS2, COQ2, COQ6, COQ9, CABC1/ADCK3) underlies the importance of these conditions.	coenzyme Q10	61-68	decaprenyl diphosphate synthase subunit 2	Homo sapiens	99-104	
18230681-2	2008	Last year, we reported the first mutations in CoQ(10) biosynthetic genes, COQ2, which encodes 4-parahydroxybenzoate: polyprenyl transferase; and PDSS2, which encodes subunit 2 of decaprenyl diphosphate synthase.	coenzyme Q10	46-53	decaprenyl diphosphate synthase subunit 2	Homo sapiens	166-210	
18230681-6	2008	PDSS2 mutant fibroblasts have 12% CoQ(10) relative to control cells and markedly reduced ATP synthesis, but do not show increased reactive oxygen species (ROS) production, signs of oxidative stress, or increased antioxidant defense markers.	coenzyme Q10	34-37	decaprenyl diphosphate synthase subunit 2	Homo sapiens	0-5	
23150520-1	2013	Primary human CoQ(10) deficiencies are clinically heterogeneous diseases caused by mutations in PDSS2 and other genes required for CoQ(10) biosynthesis.	coenzyme Q10	14-21	decaprenyl diphosphate synthase subunit 2	Homo sapiens	96-101	
23150520-1	2013	Primary human CoQ(10) deficiencies are clinically heterogeneous diseases caused by mutations in PDSS2 and other genes required for CoQ(10) biosynthesis.	coenzyme Q10	131-138	decaprenyl diphosphate synthase subunit 2	Homo sapiens	96-101	
33285023-5	2021	The visual system seems to be mainly involved when the first steps of CoQ10 synthesis are impaired (PDSS1, PDSS2, and COQ2 deficiency).	coenzyme Q10	70-75	decaprenyl diphosphate synthase subunit 2	Homo sapiens	107-112