PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30881598-10 2019 A rescue experiment using specific inhibitors of the PI3K-AKT-mTOR pathway demonstrated that the PI3K-AKT-mTOR signaling pathway was the underlying mechanism by which CoQ10 ameliorated fibrosis. coenzyme Q10 167-172 mechanistic target of rapamycin kinase Mus musculus 62-66 30881598-10 2019 A rescue experiment using specific inhibitors of the PI3K-AKT-mTOR pathway demonstrated that the PI3K-AKT-mTOR signaling pathway was the underlying mechanism by which CoQ10 ameliorated fibrosis. coenzyme Q10 167-172 mechanistic target of rapamycin kinase Mus musculus 106-110 29190916-11 2017 Conclusions: Our finding suggests that CoQ10 inhibits the activation of PSCs by suppressing autophagy through activating the PI3K/AKT/mTOR signaling pathway. coenzyme Q10 39-44 mechanistic target of rapamycin kinase Mus musculus 134-138