PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11410806-5 2001 RT-PCR analysis indicated that exposure to Leydig cells to 1 pg/ml and 100 ng/ml 17alpha-estradiol resulted in a 10- and 5-fold increases in the expression of ERalpha, respectively. alfatradiol 81-98 estrogen receptor 1 (alpha) Mus musculus 159-166 33289482-0 2020 Health benefits attributed to 17alpha-estradiol, a lifespan-extending compound, are mediated through estrogen receptor alpha. alfatradiol 30-47 estrogen receptor 1 (alpha) Mus musculus 101-124 10684871-6 2000 Interestingly, the transcriptionally inactive stereoisomer 17alpha-estradiol did elicit a strong induction of ERK phosphorylation, which, together with the inability of the ER-alpha- and ER-beta-selective ligands to elicit ERK phosphorylation, and of ICI 182,780 to block the actions of estradiol in ERKO cultures, supports the hypothesis that a novel, estradiol-sensitive and ICI-insensitive estrogen receptor may mediate 17beta-estradiol-induced activation of ERK in the brain. alfatradiol 59-76 estrogen receptor 1 (alpha) Mus musculus 393-410 33289482-5 2020 Herein, we show that 17alpha-estradiol elicits similar genomic binding and transcriptional activation through estrogen receptor alpha (ERalpha) to that of 17beta-estradiol. alfatradiol 21-38 estrogen receptor 1 (alpha) Mus musculus 110-133 33289482-5 2020 Herein, we show that 17alpha-estradiol elicits similar genomic binding and transcriptional activation through estrogen receptor alpha (ERalpha) to that of 17beta-estradiol. alfatradiol 21-38 estrogen receptor 1 (alpha) Mus musculus 135-142