PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34710829-4 2021 Here, we adopted a prodrug system that uses 5-fluorocytosine (5-FC) and a HER2-targeting scaffold protein, ZHER2:2891, fused with yeast cytosine deaminase (Fcy) to target HER2-overexpressing cancer cells and to convert 5-FC to a significantly more toxic chemotherapeutic, 5-fluorouracil (5-FU). Flucytosine 44-60 glutamyl-tRNA(Gln) amidotransferase subunit HER2 Saccharomyces cerevisiae S288C 171-175 34710829-4 2021 Here, we adopted a prodrug system that uses 5-fluorocytosine (5-FC) and a HER2-targeting scaffold protein, ZHER2:2891, fused with yeast cytosine deaminase (Fcy) to target HER2-overexpressing cancer cells and to convert 5-FC to a significantly more toxic chemotherapeutic, 5-fluorouracil (5-FU). Flucytosine 62-66 glutamyl-tRNA(Gln) amidotransferase subunit HER2 Saccharomyces cerevisiae S288C 171-175 34710829-4 2021 Here, we adopted a prodrug system that uses 5-fluorocytosine (5-FC) and a HER2-targeting scaffold protein, ZHER2:2891, fused with yeast cytosine deaminase (Fcy) to target HER2-overexpressing cancer cells and to convert 5-FC to a significantly more toxic chemotherapeutic, 5-fluorouracil (5-FU). Flucytosine 219-223 glutamyl-tRNA(Gln) amidotransferase subunit HER2 Saccharomyces cerevisiae S288C 74-78