PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25708117-10	2015	Intestinal epithelial cells represent a direct target of the action of olive oil phenols where they regulate IL-8 expression by transcriptional and posttranscriptional mechanisms.	Phenols	81-88	C-X-C motif chemokine ligand 8	Homo sapiens	109-113	
27436995-5	2016	RESULTS: At the non-toxic dosages, chemical compounds belonging to nicotine, aromatic amines, benzopyrene, phenols, aldehydes, and some other volatile organics dose-dependently increased IL-8 reporter gene expression.	Phenols	107-114	C-X-C motif chemokine ligand 8	Homo sapiens	187-191	
27436995-6	2016	Consistently, the representative compounds belonging to nicotine, aromatic amines, benzopyrene, phenols, aldehydes, and some other volatile organics significantly and dose-dependently increased IL-8 levels in the culture supernatants of 16HBE cells, among these compounds, benzopyrene is a most potent stimulator for inducing IL-8 production.	Phenols	96-103	C-X-C motif chemokine ligand 8	Homo sapiens	194-198	
27436995-6	2016	Consistently, the representative compounds belonging to nicotine, aromatic amines, benzopyrene, phenols, aldehydes, and some other volatile organics significantly and dose-dependently increased IL-8 levels in the culture supernatants of 16HBE cells, among these compounds, benzopyrene is a most potent stimulator for inducing IL-8 production.	Phenols	96-103	C-X-C motif chemokine ligand 8	Homo sapiens	326-330	
22696056-0	2012	Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8.	Phenols	18-25	C-X-C motif chemokine ligand 8	Homo sapiens	117-120	
22696056-9	2012	Co-treatment with XBP1 inhibitors reduced IL6 and IL8 production induced by phenols, while overexpression of XBP1 alone increased their expression.	Phenols	76-83	C-X-C motif chemokine ligand 8	Homo sapiens	50-53	
10951249-5	2000	Variable release of tumor necrosis factor-alpha and interleukin-8 from keratinocytes occurred only at toxic threshold concentrations of the phenols or sodium dodecyl sulfate.	Phenols	140-147	C-X-C motif chemokine ligand 8	Homo sapiens	52-65	
23069909-5	2012	report the upregulation of IL-6 and IL-8 after the activation of the unfolded protein response (UPR) following exposure of melanocytes to phenols.	Phenols	138-145	C-X-C motif chemokine ligand 8	Homo sapiens	36-40