PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18310964-9 2008 Plasma insulin as well as fibrinogen were significantly reduced by delapril/manidipine (-17.8 pmol/l, p=0.047 and -67.5 mg/dl, p=0.021, respectively), but not by olmesartan/HCTZ, the difference between the two treatments being statistically significant (p <0.05). delapril 67-75 insulin Homo sapiens 7-14 18310964-10 2008 CONCLUSION: In obese hypertensive patients the delapril/manidipine combination but not the olmesartan/HCTZ combination significantly decreased insulin resistance and plasma fibrinogen levels, despite the similar BP lowering efficacy. delapril 47-55 insulin Homo sapiens 143-150 8877275-0 1996 Effect of manidipine and delapril on insulin sensitivity in type 2 diabetic patients with essential hypertension. delapril 25-33 insulin Homo sapiens 37-44 18310964-0 2008 Effect of delapril/manidipine vs olmesartan/ hydrochlorothiazide combination on insulin sensitivity and fibrinogen in obese hypertensive patients. delapril 10-18 insulin Homo sapiens 80-87 8877275-1 1996 The open trial was designed to evaluate the effects of long-term antihypertensive treatment with the calcium-channel blocker, manidipine and the angiotensin converting enzyme (ACE) inhibitor, delapril on insulin sensitivity in Japanese non-insulin dependent diabetes mellitus (NIDDM) patients with essential hypertension. delapril 192-200 insulin Homo sapiens 204-211 8174845-4 1994 In comparison, intravenous administration of an active metabolite of delapril (3.0 mmol.kg-1) and oral administration of either delapril or enalapril (5.0 mmol.kg-1) showed slight, but not significant increases in insulin sensitivity indices and plasma bradykinin concentrations. delapril 69-77 insulin Homo sapiens 214-221