PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31658639-2 2019 The binding of two Ca2+ ions to the functional EF-hand motifs induces the extrusion of a myristoyl group that increases the affinity of Rec for the membrane and leads to the formation of a complex with rhodopsin kinase (GRK1). S-tetradecanoyl-coenzyme A 89-98 G protein-coupled receptor kinase 1 Homo sapiens 202-218 31658639-5 2019 In particular, salt bridges between Arg43, Arg46 and polar heads of phosphatidylserine lipids are necessary to enhance the myristoyl hydrophobic packing in the Rec-GRK1 assembly. S-tetradecanoyl-coenzyme A 123-132 G protein-coupled receptor kinase 1 Homo sapiens 164-168 31658639-2 2019 The binding of two Ca2+ ions to the functional EF-hand motifs induces the extrusion of a myristoyl group that increases the affinity of Rec for the membrane and leads to the formation of a complex with rhodopsin kinase (GRK1). S-tetradecanoyl-coenzyme A 89-98 G protein-coupled receptor kinase 1 Homo sapiens 220-224 31658639-3 2019 Here, unbiased all-atom molecular dynamics simulations were performed to monitor the spontaneous insertion of the myristoyl group into a model multicomponent biological membrane for both isolated Rec and for its complex with a peptide from the GRK1 target. S-tetradecanoyl-coenzyme A 114-123 G protein-coupled receptor kinase 1 Homo sapiens 244-248