PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32568-1	1978	The subsynaptic area of mouse diaphragm fibres was hyperpolarized by 1--2 mV during local curarization of the junctional zone in the presence of the reversible anticholinesteraze prostigmine (6 X 10(-6) M), or after treatment of the muscle with organophosphate cholinesterase inhibitor Soman.	Neostigmine	179-190	butyrylcholinesterase	Mus musculus	261-275	
19486927-6	2009	Ca(2+) transients were evoked by electrical stimulation of intrinsic nerves in the presence of the cholinesterase inhibitor neostigmine (10 microM).	Neostigmine	124-135	butyrylcholinesterase	Mus musculus	99-113	
16582934-13	2006	The cholinesterase inhibitor neostigmine (0.3 ng, i.t.)	Neostigmine	29-40	butyrylcholinesterase	Mus musculus	4-18	
12522088-4	2003	Inhibition of both AChE and BChE with galanthamine (80 micro M), neostigmine (3-10 micro M), O-ethylS-2-(diisopropylamino)ethyl-methylphosphono-thioate (MTP) or phospholine decreased evoked transmitter release (20-50%).	Neostigmine	65-76	butyrylcholinesterase	Mus musculus	28-32	
8499198-3	1993	In the mouse diaphragm nerve-muscle preparations, neostigmine 1 mumol litre-1 continued to produce some antagonism of tubocurarine-induced block after cholinesterase had been inactivated completely by diisopropyl fluorophosphate 22 mumol litre-1.	Neostigmine	50-61	butyrylcholinesterase	Mus musculus	151-165	
8499198-7	1993	Although inhibition of acetyl-cholinesterase is the main mechanism of action of neostigmine, the drug also exerts an additional direct action on motor nerve endings to block the delayed rectifier K+ channels and enhance transmitter release.	Neostigmine	80-91	butyrylcholinesterase	Mus musculus	30-44	
6354300-0	1983	[Trial of cholinesterase reactivators as proserine antagonists].	Neostigmine	41-50	butyrylcholinesterase	Mus musculus	10-24	
6286926-8	1982	Neostigmine, a selective peripheral cholinesterase inhibitor, induced respiratory paralysis which was not affected by clonidine pretreatment.	Neostigmine	0-11	butyrylcholinesterase	Mus musculus	36-50	
18091537-10	2008	Animals treated with the peripheral cholinesterase inhibitor neostigmine showed no difference compared with physostigmine-treated animals.	Neostigmine	61-72	butyrylcholinesterase	Mus musculus	36-50	
10952694-2	2000	Both acetylcholine (100 microM) and the cholinesterase inhibitor neostigmine (100 microM) inhibited the stimulation-induced (S-I) outflow of radioactivity but in the presence of atropine (0.3 microM) an enhancement was seen, which may be indicative of facilitatory nicotinic receptors.	Neostigmine	65-76	butyrylcholinesterase	Mus musculus	40-54	
3617097-1	1987	Physostigmine (1.5 mg/kg, s.c.) and neostigmine (1.0 mg/kg, s.c.) injection into male mice produced signs of toxicosis characteristic of cholinesterase inhibition and evoked death in 95 and 94% of the animals respectively.	Neostigmine	36-47	butyrylcholinesterase	Mus musculus	137-151	
26499847-5	2015	The cholinesterase inhibitor neostigmine mimicked the effects of electroacupuncture on HMGB1 release and myocardial ischemia reperfusion injury.	Neostigmine	29-40	butyrylcholinesterase	Mus musculus	4-18	
975633-4	1976	A combination of reserpine plus a cholinesterase inhibitor significantly increased lethality in adult male Swiss-Webster mice above that caused by either neostigmine, physostigmine, or reserpine alone.	Neostigmine	154-165	butyrylcholinesterase	Mus musculus	34-48	
28749013-13	2017	In the presence of the cholinesterase inhibitor neostigmine, EFS led to an additional increase in phosphorylation of MYPT1 T853, MYPT1 T696, MBS85 and paxillin.	Neostigmine	48-59	butyrylcholinesterase	Mus musculus	23-37	
22803143-1	2012	Experiments on outbred albino mice have shown that proserine (reversible cholinesterase inhibitor) and nicotine (nicotinic receptor agonist) in a equivalent dose of 0.2 DL(50)injected 2 h before sepsis induction significantly reduced animal mortality from experimental infection due to reduction of blood concentrations of proinflammatory cytokines TNF-alpha, IL-1beta, and IL-6.	Neostigmine	51-60	butyrylcholinesterase	Mus musculus	73-87