PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2571183-5 1989 The stimulatory influence of norepinephrine, serotonin, and acetylcholine on the secretion of corticotropin (ACTH) in rodents and man will be discussed, whereas GABA exerts an inhibitory effect on the secretion of ACTH in both man and rodents. Norepinephrine 29-43 proopiomelanocortin Homo sapiens 109-113 19210461-0 1989 Corticotrophin-Releasing Factor Antagonist [alpha helical CRF(9-41)] Blocks Central Noradrenaline-lnduced ACTH Secretion. Norepinephrine 84-97 proopiomelanocortin Homo sapiens 106-110 19210461-1 1989 Plasma ACTH increased after an intra-third ventricular administration of noradrenaline (NA). Norepinephrine 73-86 proopiomelanocortin Homo sapiens 7-11 2567554-4 1989 The release of ACTH is controlled by two stimulating hormones, the ACTH releasing factor and vasopressin, the effects of neurotransmitters are less marked, with the involvement of noradrenaline, serotonin, acetylcholine, gamma aminobutyric acid and other agents. Norepinephrine 180-193 proopiomelanocortin Homo sapiens 15-19 3241222-2 1988 In the present study plasma concentrations of the opioid peptide beta-endorphin were significantly lower at rest in young subjects with essential hypertension and high plasma noradrenaline (n = 9) than in normotensive controls (n = 13, P less than 0.05). Norepinephrine 175-188 proopiomelanocortin Homo sapiens 65-79 2850915-7 1988 In congenital HGH and ACTH deficiency, the low basal plasma levels of noradrenaline (0.12 ng/ml) and adrenaline (0.01 ng/ml) remained unchanged in response to hypoglycaemia. Norepinephrine 70-83 proopiomelanocortin Homo sapiens 22-26 3326056-7 1987 By immunocytochemistry gamma 2-MSH immunoreactivity was localized to the adrenocorticotropin/alpha-MSH cells in the pituitary and to a subpopulation of the noradrenaline-storing cells in the adrenal medulla. Norepinephrine 156-169 proopiomelanocortin Homo sapiens 31-34 2850308-6 1988 It appears that the acute cardiovascular response to gamma-MSH administration depends primarily on the release of sympathetic terminal norepinephrine, though some contribution from other pressor systems such as adrenal catecholamines is possible. Norepinephrine 135-149 proopiomelanocortin Homo sapiens 53-62 2837885-10 1988 These results suggest the etiologic possibility that the patients have a decreased dopaminergic inhibition of prostaglandin E2-mediated norepinephrine secretion, which causes periodic discharge of norepinephrine and concomitant release of ACTH and AVP. Norepinephrine 136-150 proopiomelanocortin Homo sapiens 239-243 2899848-8 1988 Results of this study support the hypothesis that epinephrine and/or norepinephrine regulate the release of ACTH and vasopressin via alpha-1- and alpha-2-adrenergic receptors associated with CRF- and VP-containing somata within the PVN. Norepinephrine 69-83 proopiomelanocortin Homo sapiens 108-112 2942391-2 1986 An injection of synthetic human beta-endorphin (20 micrograms/kg BW) into a cephalic vein produced a significant rise in the portal concentration of dopamine, norepinephrine, and epinephrine. Norepinephrine 159-173 proopiomelanocortin Homo sapiens 32-46 2826568-4 1987 beta-Endorphin also markedly increased plasma concentrations of epinephrine, norepinephrine and, to a lesser extent, dopamine. Norepinephrine 77-91 proopiomelanocortin Homo sapiens 0-14 2826868-2 1987 The individuals of behavioral type A showed significantly increased noradrenaline excretion with daily urine and serum ACTH levels. Norepinephrine 68-81 proopiomelanocortin Homo sapiens 119-123 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 0-14 proopiomelanocortin Homo sapiens 48-62 3015341-1 1986 The size of miniature end-plate potentials (m.e.p.p.s) and miniature end-plate currents (m.e.p.c.s) at frog neuromuscular junctions was increased by a factor of two or more following treatment with norepinephrine, epinephrine, a cAMP derivative, insulin or ACTH. Norepinephrine 198-212 proopiomelanocortin Homo sapiens 257-261 2940358-8 1986 administration of norepinephrine with beta-endorphin blunted the plasma epinephrine response to i.c. Norepinephrine 18-32 proopiomelanocortin Homo sapiens 38-52 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 0-14 proopiomelanocortin Homo sapiens 129-143 2940358-15 1986 norepinephrine on beta-endorphin-induced catecholamine secretion. Norepinephrine 0-14 proopiomelanocortin Homo sapiens 18-32 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 168-182 proopiomelanocortin Homo sapiens 48-62 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 168-182 proopiomelanocortin Homo sapiens 129-143 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 168-182 proopiomelanocortin Homo sapiens 48-62 2940358-17 1986 norepinephrine at a dose insufficient to reduce beta-endorphin-induced catecholamine secretion in vehicle-treated rats prevented beta-endorphin-induced epinephrine and norepinephrine secretion in rats whose brains had been depleted of norepinephrine by prior 6-OHDA treatment. Norepinephrine 168-182 proopiomelanocortin Homo sapiens 129-143 3031718-16 1986 The findings of these trials, especially those of the prazosin trial, indicate that DMI-induced stimulation of cortisol and ACTH secretion is attributable to the noradrenaline (NA) reuptake inhibiting effect of DMI, and that the stimulus is transmitted with the aid of noradrenergic alpha-1 receptors. Norepinephrine 162-175 proopiomelanocortin Homo sapiens 124-128 3000912-0 1986 ACTH stimulation of adrenal epinephrine and norepinephrine release. Norepinephrine 44-58 proopiomelanocortin Homo sapiens 0-4 6299918-4 1983 The pre-existing paradoxical ACTH response of patients with Cushing"s disease after adrenalectomy was abolished after depletion of norepinephrine granules by means of reserpine. Norepinephrine 131-145 proopiomelanocortin Homo sapiens 29-33 2860247-3 1985 The longlasting signal generated by the covalent MSH-receptor complex was readily and reversibly abolished by adrenaline, noradrenaline, dopamine or clonidine or by the absence of calcium. Norepinephrine 122-135 proopiomelanocortin Homo sapiens 49-52 2860247-5 1985 Forskolin, which stimulates melanophores by direct action on the catalytic unit of the adenylate cyclase and at about the same speed as alpha-MSH, produced a slower and weaker response in the presence of noradrenaline. Norepinephrine 204-217 proopiomelanocortin Homo sapiens 136-145 2860247-6 1985 If MSH receptors were covalently labelled and then exposed to noradrenaline, the characteristics of the forskolin-induced response were identical to those of unlabelled cells that had not been exposed to noradrenaline. Norepinephrine 62-75 proopiomelanocortin Homo sapiens 3-6 3929669-14 1985 We have demonstrated that, in amphibians, dopamine inhibits alpha-MSH secretion through D2-type dopaminergic receptors whereas norepinephrine and (or) epinephrine stimulate alpha-MSH secretion via beta-adrenergic receptors. Norepinephrine 127-141 proopiomelanocortin Homo sapiens 173-182 6280799-5 1982 3 alpha-MSH dose-response curves were shifted, in parallel, to the right in the presence of the catecholamines, noradrenaline, adrenaline and dopamine, and Lineweaver-Burke plots and Arunlakshana-Schild plots indicated that the catecholamines antagonized MSH action by a competitive mechanism. Norepinephrine 112-125 proopiomelanocortin Homo sapiens 2-11 6306616-4 1983 Simultaneous intracisternal administration of angiotensin II 1.0 nmol together with synthetic human beta-endorphin 1.45 nmol potentiated the plasma epinephrine, norepinephrine and dopamine responses to intracisternal beta-endorphin. Norepinephrine 161-175 proopiomelanocortin Homo sapiens 100-114 6281410-3 1982 Perfusion of spleens with Met-enkephalin (10(-8)-10(-5) M) produced a dose-dependent decrease in the release of endogenous norepinephrine upon nerve stimulation. Norepinephrine 123-137 proopiomelanocortin Homo sapiens 26-40 6317800-4 1983 Moreover, by itself, ACTH treatment alters the ability of norepinephrine to stimulate cAMP accumulation in brain tissue without affecting recognition site number. Norepinephrine 58-72 proopiomelanocortin Homo sapiens 21-25 6751813-6 1982 Peak levels of norepinephrine (228.9 +/- 36.0 ng/l) and epinephrine (720.6 +/- 125.6 ng/l) are observed at 30 and 45 min, those of cAMP (33.4 +/- 2.5 pmol/ml), glucagon (0.209 +/- 0.024 ng/ml), ACTH (166.0 +/- 40.1 ng/ml), and prolactin (28.1 +/- 7.8 ng/ml) at 45 min and finally those of cortisol (26.1 +/- 3.3 micrograms/100 ml) and growth hormone (21.6 +/- 3.1 ng/ml) at 60 min following insulin injection. Norepinephrine 15-29 proopiomelanocortin Homo sapiens 194-198 6281410-9 1982 These findings support the hypothesis that the opiate receptor population in peripheral tissues are heterogenous and that Met-enkephalin depresses exocytotic release of norepinephrine by interacting with a specific presynaptic opiate receptor. Norepinephrine 169-183 proopiomelanocortin Homo sapiens 122-136 6263592-0 1981 beta-Endorphin-induced stimulation of central sympathetic outflow: beta-endorphin increases plasma concentrations of epinephrine, norepinephrine, and dopamine in rats. Norepinephrine 130-144 proopiomelanocortin Homo sapiens 67-81 6266596-9 1981 The action of ACTH on protein synthesis rate might be mediated by a calcium-dependent release of norepinephrine followed postsynaptically by beta-receptor activation, cAMP production, and stimulation of translation. Norepinephrine 97-111 proopiomelanocortin Homo sapiens 14-18 6263592-1 1981 Intracisternal administration of synthetic human beta-endorphin (0.058-7.25 nmol) in chronically cannulated, conscious, freely moving, adult male rats increased plasma concentrations of epinephrine, norepinephrine, and dopamine in a dose-related manner. Norepinephrine 199-213 proopiomelanocortin Homo sapiens 49-63 185101-13 1976 Using this method, it found that LVP, AVP, norepinephrine (100 ng/ml200 ng/ml) and 5-hydroxytryptophane (1 mug/ml) had ACTH releasing activities but LH-RH, TRH, glucagon, dopamine, phentolamine, propranolol, haloperidol, prostaglandin E1 and indomethacin did not affect the release of ACTH. Norepinephrine 43-57 proopiomelanocortin Homo sapiens 119-123 224071-5 1979 In the thymic tumor cells, norepinephrine, serotonin, and TRH were found to be effective in increasing ACTH secretion and intracellular cAMP levels, whereas biogenic amines, hypothalamic hormones, and gastrointestinal hormones did not affect hormone secretion in the thyroid tumor cells. Norepinephrine 27-41 proopiomelanocortin Homo sapiens 103-107 215466-3 1978 This suggests different mechanisms of ACTH and adrenaline effects upon UEF: the stimulating effect of noradrenaline is realized through thrombinogenesis followed by activation of the ACS function and by an increase of UEF and therefore inhibitable by hirudin which form an inactive complex with thrombin. Norepinephrine 102-115 proopiomelanocortin Homo sapiens 38-42 190256-8 1977 The adenylate cyclase of two ectopic ACTH producing tumors (gastric carcinoid and malignant thymoma) was activated by TRH, LH-RH, norepinephrine, epinephrine, serotonin, PGE1 and MEE. Norepinephrine 130-144 proopiomelanocortin Homo sapiens 37-41 825886-4 1976 These significant changes after alpha-MSH were of a much smaller magnitude than were observed after prostaglandins E1 and E2, isoproterenol, bradykinin or glyceryl trinitrate and differed completely from the increased resistance after angiotensin II and norepinephrine. Norepinephrine 254-268 proopiomelanocortin Homo sapiens 32-41 6112047-0 1981 Beta-endorphin-induced increases in plasma epinephrine, norepinephrine and dopamine in rats: inhibition of adrenomedullary response by intracerebral somatostatin. Norepinephrine 56-70 proopiomelanocortin Homo sapiens 0-14 6112047-1 1981 Synthetic human beta-endorphin, 7.25 nmol intracisternally, in unanesthetized, freely moving, chronically cannulated, adult male rats increased plasma concentrations of all 3 catecholamines: epinephrine, norepinephrine and dopamine, for the 2 h period studied. Norepinephrine 204-218 proopiomelanocortin Homo sapiens 16-30 6112047-3 1981 Acute systemic administration of guanethidine, which decreases norepinephrine release induced by sympathetic nerve stimulation, blunted the plasma norepinephrine response to intracerebral beta-endorphin. Norepinephrine 63-77 proopiomelanocortin Homo sapiens 188-202 6112047-3 1981 Acute systemic administration of guanethidine, which decreases norepinephrine release induced by sympathetic nerve stimulation, blunted the plasma norepinephrine response to intracerebral beta-endorphin. Norepinephrine 147-161 proopiomelanocortin Homo sapiens 188-202 6112047-4 1981 Thus, it seems likely that in addition to secretion by adrenal medulla a considerable portion of the beta-endorphin-induced increase in norepinephrine is derived from sympathetic nerve endings. Norepinephrine 136-150 proopiomelanocortin Homo sapiens 101-115 6112047-5 1981 Simultaneous intracisternal administration of another neuropeptide, somatostatin, together with beta-endorphin markedly inhibited the plasma epinephrine response to beta-endorphin, while decreasing the dopamine and norepinephrine responses to a much lesser degree. Norepinephrine 215-229 proopiomelanocortin Homo sapiens 96-110 6254640-3 1980 Of five ACTH-responsive adrenocortical adenomas, in contrast, three were stimulated by norepinephrine, two by epinephrine, one by thyroid-stimulating hormone, and one by luteinizing hormone in addition to ACTH, indicating the presence of multiple receptors for hormones other than ACTH and PGE1 in these four tumors. Norepinephrine 87-101 proopiomelanocortin Homo sapiens 8-12 185101-13 1976 Using this method, it found that LVP, AVP, norepinephrine (100 ng/ml200 ng/ml) and 5-hydroxytryptophane (1 mug/ml) had ACTH releasing activities but LH-RH, TRH, glucagon, dopamine, phentolamine, propranolol, haloperidol, prostaglandin E1 and indomethacin did not affect the release of ACTH. Norepinephrine 43-57 proopiomelanocortin Homo sapiens 285-289 22170706-8 2012 Subjects with an exercise-induced rise in beta-endorphin levels to above 25 pg/ml (n = 7) exhibited markedly reduced levels of plasma epinephrine and norepinephrine compared with control (2495 +- 306 vs. 4810 +- 617 pmol/liter and 1.9 +- 0.3 vs. 2.9 +- 0.4 nmol/liter, respectively, P < 0.01 for both). Norepinephrine 150-164 proopiomelanocortin Homo sapiens 42-56 4351773-0 1973 Effect of hypopituitarism and ACTH on the urinary excretion of norepinephrine in man. Norepinephrine 63-77 proopiomelanocortin Homo sapiens 30-34 29308764-3 2018 The hypothalamus-pituitary-adrenal cortical (HPA) axis and sympathetic-adrenal medulla axis were activated and participated the initiation and progression of the stress response through the production of adrenocorticotropic hormone (ACTH), glucocorticoid (GC), epinephrine and norepinephrine (NE). Norepinephrine 277-291 proopiomelanocortin Homo sapiens 204-231 29308764-3 2018 The hypothalamus-pituitary-adrenal cortical (HPA) axis and sympathetic-adrenal medulla axis were activated and participated the initiation and progression of the stress response through the production of adrenocorticotropic hormone (ACTH), glucocorticoid (GC), epinephrine and norepinephrine (NE). Norepinephrine 277-291 proopiomelanocortin Homo sapiens 233-237 23276607-6 2013 PFC tissue from ACTH pre-treated animals contained significantly higher serotonin, noradrenaline and adrenaline concentrations relative to saline pre-treated controls. Norepinephrine 83-96 proopiomelanocortin Homo sapiens 16-20 18064421-4 2008 Presynaptic receptors for ACTH (MC(2) receptors) have so far been identified almost exclusively in cardiovascular tissues from rabbits, where they facilitate noradrenaline release; they are coupled to G(s) protein and act via stimulation of adenylyl cyclase. Norepinephrine 158-171 proopiomelanocortin Homo sapiens 26-30 18440707-3 2008 To analyze further the involvement of ACTH in regulation of gene expression of norepinephrine (NE) biosynthetic enzymes, we examined the effect of bilateral adrenalectomy (ADX) of Sprague-Dawley male rats. Norepinephrine 79-93 proopiomelanocortin Homo sapiens 38-42 17280595-1 2007 Noradrenaline or serotonin (5-HT) reuptake-inhibiting antidepressants such as reboxetine or citalopram acutely stimulate cortisol and adrenocorticotrophic hormone (ACTH) secretion in healthy volunteers, whereas mirtazapine acutely inhibits the ACTH and cortisol release, probably due to its antagonism at central 5-HT(2) and/or H(1) receptors. Norepinephrine 0-13 proopiomelanocortin Homo sapiens 164-168 17280595-1 2007 Noradrenaline or serotonin (5-HT) reuptake-inhibiting antidepressants such as reboxetine or citalopram acutely stimulate cortisol and adrenocorticotrophic hormone (ACTH) secretion in healthy volunteers, whereas mirtazapine acutely inhibits the ACTH and cortisol release, probably due to its antagonism at central 5-HT(2) and/or H(1) receptors. Norepinephrine 0-13 proopiomelanocortin Homo sapiens 244-248 16138261-7 2005 Thirty minutes after IN or IV administration of ACTH(1-24), plasma norepinephrine levels increased by 55.9 +/- 13.4 % and 73.7 +/- 15.0 %, respectively, peaking 30 min after ACTH(1-24) administration, and decreasing to basal levels within 60 min. Norepinephrine 67-81 proopiomelanocortin Homo sapiens 48-52 15956086-6 2005 In controls, beta-endorphin reduced blood pressure (P < 0.01) and circulating norepinephrine (P < 0.02) and increased plasma atrial natriuretic factor (P < 0.003) and GH (P < 0.0001). Norepinephrine 81-95 proopiomelanocortin Homo sapiens 13-27 15956086-7 2005 In hypertensive patients, beta-endorphin decreased systemic vascular resistance (P < 0.0001), blood pressure (P < 0.0001), and plasma norepinephrine (P < 0.0001) and endothelin-1 (P < 0.0001) and raised circulating atrial natriuretic factor (P < 0.0001), GH (P < 0.0001), and IGF-I (P < 0.0001). Norepinephrine 140-154 proopiomelanocortin Homo sapiens 26-40 16138261-10 2005 These results demonstrate that IN administration of ACTH(1-24) not only stimulates adrenocortical steroids, but also epinephrine and norepinephrine. Norepinephrine 133-147 proopiomelanocortin Homo sapiens 52-56 12009349-8 2002 RESULT(S): Low baseline levels of DA, serotonin, and beta-endorphin increased significantly (P<.001) from 181.9 +/- 47.8 pg/mL to 202.9 +/- 32.8 pg/mL (mean +/- SD); from 206.4 +/- 94.2 ng/mL to 279.2 +/- 67.9 ng/mL; from 11.2 +/- 1.8 pmol/L to 13.8 +/- 2.4 pmol/L, respectively, after conjugated equine E. In parallel, augmented baseline noradrenaline levels diminished significantly (P<.05) from 30.2 +/- 4.7 ng/mL to 24.0 +/- 4.7 ng/mL. Norepinephrine 342-355 proopiomelanocortin Homo sapiens 53-67 16019595-2 2005 Several contributing factors have been proposed for this phenomenon in lactation, including the suckling stimulus from the pups, hormones (oxytocin and prolactin) and opioids, a decrease in the ability of noradrenaline to potentiate hypothalamic responses and changes in pituitary responsiveness to ACTH secretagogues (AVP and CRF). Norepinephrine 205-218 proopiomelanocortin Homo sapiens 299-303 12889599-4 2003 Our results show that met-enkephalin, substance P, bombesin, dopamine, and norepinephrine have a stimulatory effect on the migration of the breast cancer cells; moreover, these cells show positive chemotaxis towards norepinephrine as was analyzed by the directionality and persistence on a single-cell basis. Norepinephrine 216-230 proopiomelanocortin Homo sapiens 22-36 9438155-9 1996 beta-endorphin IRM concentrations were correlated negatively to heart rate (-0.55; p < 0.0005) and positively to the noradrenaline concentration (0.56; p < 0.0004). Norepinephrine 120-133 proopiomelanocortin Homo sapiens 0-14 11316770-2 2001 Stress activates A1/A2 noradrenergic neurons, and then noradrenaline (NA) stimulates ACTH secretion through hypothalamic CRH. Norepinephrine 55-68 proopiomelanocortin Homo sapiens 85-89 9288827-7 1997 These results indicate that beta-endorphin acts on mu-opioid receptors to inhibit K+-evoked norepinephrine release from A2 neurons and suggest that the receptors involved are not located on noradrenergic nerve terminals. Norepinephrine 92-106 proopiomelanocortin Homo sapiens 28-42 8995987-12 1997 CONCLUSIONS: In patients with congestive heart failure, the net release of plasma beta-endorphin during exercise is decreased, like norepinephrine, and reflects a functional disability. Norepinephrine 132-146 proopiomelanocortin Homo sapiens 82-96 9288827-0 1997 Beta-endorphin inhibition of endogenous norepinephrine release from the A2 noradrenergic nucleus in vitro: role of mu opiate receptors and Na+ ion permeability. Norepinephrine 40-54 proopiomelanocortin Homo sapiens 0-14 9288827-1 1997 An in vitro approach was used to determine the opioid receptor subtype mediating beta-endorphin inhibition of endogenous norepinephrine release from the A2 nucleus in the caudal dorsomedial medulla of rats. Norepinephrine 121-135 proopiomelanocortin Homo sapiens 81-95 9288827-2 1997 The voltage-sensitive Na+ channel blocker tetrodotoxin was used to investigate the role of Na+-dependent action potentials in beta-endorphin inhibition of K+-evoked norepinephrine release. Norepinephrine 165-179 proopiomelanocortin Homo sapiens 126-140 9288827-3 1997 Human beta-endorphin(1-31) inhibited K+-evoked norepinephrine release in a concentration-dependent fashion. Norepinephrine 47-61 proopiomelanocortin Homo sapiens 6-20 9438155-12 1996 CONCLUSION: It is concluded that beta-endorphin IRM concentration in the plasma is linked to epinephrine and norepinephrine concentrations under intensive care conditions. Norepinephrine 109-123 proopiomelanocortin Homo sapiens 33-47 8917909-2 1996 Generally, in anestrous ewes beta-endorphin and/or corticoliberin significantly change extracellular concentrations of monoamine metabolites in the MBH-ME, but in estrous ewes both beta-endorphin and CRF alters also dopamine, noradrenaline and serotonin levels. Norepinephrine 226-239 proopiomelanocortin Homo sapiens 29-43 8917909-2 1996 Generally, in anestrous ewes beta-endorphin and/or corticoliberin significantly change extracellular concentrations of monoamine metabolites in the MBH-ME, but in estrous ewes both beta-endorphin and CRF alters also dopamine, noradrenaline and serotonin levels. Norepinephrine 226-239 proopiomelanocortin Homo sapiens 181-195 7520295-9 1993 beta-endorphin, which may be the "missing link" between the neuron and the wall of the arteriole, must be considered as being a fundamental neurotransmitter in the same way as well-known substances such as noradrenaline, acetylcholine, serotonin, dopamine and the GABAergic system are also neurotransmitters. Norepinephrine 206-219 proopiomelanocortin Homo sapiens 0-14 7911815-4 1994 Chronic treatment with ACTH in infantile spasms reduces cerebrospinal fluid GABA, beta-endorphin, and somatostatin, increases norepinephrine and tyrosine, and has variable or no effect on homovanillic acid, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, histamine, and tryptophan. Norepinephrine 126-140 proopiomelanocortin Homo sapiens 23-27 8387773-8 1993 Studies on cultured anterior pituitary cells suggested that adrenaline and noradrenaline may influence the secretion of ACTH, prolactin and TSH directly at the level of the pituitary. Norepinephrine 75-88 proopiomelanocortin Homo sapiens 120-124 2169395-6 1990 Because controversy exists about the effect of DCMB as an alpha 2 adrenoreceptor antagonist in vivo, this was examined by administering norepinephrine into the third ventricle after DCMB ip; DCMB significantly reduced the ACTH response to norepinephrine 0.2 micrograms (P less than 0.05) but not to 0.5 micrograms. Norepinephrine 239-253 proopiomelanocortin Homo sapiens 222-226 2169395-9 1990 Thus, the secretion of both hypothalamic epinephrine and, to some extent, norepinephrine is involved in the ACTH response to the activation of catecholaminergic neurons in the IV. Norepinephrine 74-88 proopiomelanocortin Homo sapiens 108-112 2203597-4 1990 The increase in circulating gamma 2-MSH-LI levels preceded the elevation of the venous plasma noradrenaline level, but did not rise further with more pronounced activation of the sympathetic nervous system at the highest grade of physical activity examined. Norepinephrine 94-107 proopiomelanocortin Homo sapiens 36-39 2138208-6 1990 A significant correlation was observed between gamma 2-MSH-LI and noradrenaline, and between h-alpha ANP-LI and noradrenaline in patients with CHF. Norepinephrine 66-79 proopiomelanocortin Homo sapiens 55-58 2138208-7 1990 The present results show that gamma 2-MSH-LI is increased only in severe forms of cardiac failure, and that this change is more closely related to the increase in circulating levels of noradrenaline than to increased levels of ANP-LI or AVP-LI. Norepinephrine 185-198 proopiomelanocortin Homo sapiens 38-41