PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15518901-9 2004 Pretreatment with 6-hydroxydopamine (6-OHDA) which destroys noradrenaline neuron of descending pain inhibitory systems in the spinal cord markedly abridged the latency and augmented the duration of PACAP-induced aversive responses. Norepinephrine 60-73 adenylate cyclase activating polypeptide 1 Mus musculus 198-203 12239106-9 2002 In contrast, norepinephrine and its precursor dopamine extracted from brown adipose tissue are present at significantly lower levels in the PACAP null mice compared with controls. Norepinephrine 13-27 adenylate cyclase activating polypeptide 1 Mus musculus 140-145 12239106-10 2002 Also, PACAP null mice showed a greater loss of core body temperature compared with wild-type controls at 21 C. We conclude that under prolonged but mild cold stress, lack of PACAP results in inadequate heat production due to insufficient norepinephrine stimulation of brown adipose tissue. Norepinephrine 238-252 adenylate cyclase activating polypeptide 1 Mus musculus 6-11 25841321-6 2015 The ATX-induced increases in extracellular noradrenaline and dopamine levels were significantly higher in the prefrontal cortex of PACAP(-/-) mice compared to wild-type mice with C57BL/6J and 129S6/SvEvTac hybrid background. Norepinephrine 43-56 adenylate cyclase activating polypeptide 1 Mus musculus 131-136