PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4656611-4 1972 Bradykinin-insensitive vein and aortic strips responded with substantial increases in contractile tension when exposed to prostaglandin E(2), noradrenaline, histamine and KC1. Norepinephrine 142-155 kininogen 1 Homo sapiens 0-10 7238669-5 1981 The relaxing effect of bradykinin was investigated after maximal contraction with either prostaglandin F2 alpha, histamine or norepinephrine in 23 specimens. Norepinephrine 126-140 kininogen 1 Homo sapiens 23-33 12529-2 1976 It was shown that bradykinin in a dose of 4 mug decreased the content of norepinephrine in corpus striatum, midbrain, and cerebellum. Norepinephrine 73-87 kininogen 1 Homo sapiens 18-28 12529-7 1976 It was also shown that bradykinin increased norepinephrine uptake by the blood platelets when its level in the platelets was low, and released the absorbed norepinephrine into the medium when the level of norepinephrine was higher. Norepinephrine 44-58 kininogen 1 Homo sapiens 23-33 12529-7 1976 It was also shown that bradykinin increased norepinephrine uptake by the blood platelets when its level in the platelets was low, and released the absorbed norepinephrine into the medium when the level of norepinephrine was higher. Norepinephrine 156-170 kininogen 1 Homo sapiens 23-33 12529-7 1976 It was also shown that bradykinin increased norepinephrine uptake by the blood platelets when its level in the platelets was low, and released the absorbed norepinephrine into the medium when the level of norepinephrine was higher. Norepinephrine 156-170 kininogen 1 Homo sapiens 23-33 1012987-2 1976 A treatment with bradykinin and the low dose of amphetamine reduced the noradrenaline and enhanced the serotonin level in the striatum, and lowered the dopamine content in the cortex, while a combined treatment with the high dose of amphetamine elevated the dopamine level in the striatum and hypothalamus and depressed the serotonin level in the midbrain. Norepinephrine 72-85 kininogen 1 Homo sapiens 17-27 6801733-8 1982 Finally, histochemical studies demonstrated stimulation of uterine catecholamine levels (norepinephrine) by arachidonic acid, PGF2 alpha and bradykinin. Norepinephrine 89-103 kininogen 1 Homo sapiens 141-151 887505-2 1977 Bradykinin potentiated the action of nialamide with L-dopa, dopamine, 1,3-dimethyl-5-aminoadamantane, apomorphine and noradrenaline. Norepinephrine 118-131 kininogen 1 Homo sapiens 0-10 887505-3 1977 Spiroperidol abolished potentializing effect of bradykinin on the central action of nialamide with L-DOPA and of noradrenaline. Norepinephrine 113-126 kininogen 1 Homo sapiens 48-58 887505-4 1977 In animals receiving spiroperidol with bradykinin psychostimulatory action of noradrenaline was also not observed. Norepinephrine 78-91 kininogen 1 Homo sapiens 39-49 999466-3 1976 The influence of bradykinin and kallikrein on the action of norepinephrine, epinephrine, isoprenaline, phentolamine, propranolol, aminophylline and theophylline on blood pressure was studied. Norepinephrine 60-74 kininogen 1 Homo sapiens 17-27 11164180-9 2001 RESULTS: In vitro, BK, forskolin, and sodium nitroprusside elicited dose-dependent relaxation of norepinephrine-induced tension of isolated HCC, and AN II evoked dose-dependent contraction of the HCC strips. Norepinephrine 97-111 kininogen 1 Homo sapiens 19-21 5046102-2 1972 Norepinephrine release by bradykinin. Norepinephrine 0-14 kininogen 1 Homo sapiens 26-36 20511415-10 2010 Acetylcholine and bradykinin relaxed norepinephrine preconstrictions by approximately 20% and approximately 40%, respectively. Norepinephrine 37-51 kininogen 1 Homo sapiens 18-28 15630045-0 2005 Angiotensin-(1-7) and bradykinin in norepinephrine release in the central nervous system of hypertension. Norepinephrine 36-50 kininogen 1 Homo sapiens 22-32 14751845-4 2004 In norepinephrine-constricted vessels, incubation with N(G)-nitro-L-arginine methyl ester (L-NAME) resulted in a significant reduction in relaxation to BK. Norepinephrine 3-17 kininogen 1 Homo sapiens 152-154 15167453-6 2004 Both NPP and bradykinin increased systolic (SBP) and diastolic (DBP) blood pressures, heart rate and plasma adrenaline and noradrenaline concentrations. Norepinephrine 123-136 kininogen 1 Homo sapiens 13-23 9383175-11 1997 CONCLUSION: These data suggest that bradykinin facilitates the release of noradrenaline in human and rat atrium by activation of bradykinin receptors of the B2-subtype and subsequent release of facilitatory prostaglandins. Norepinephrine 74-87 kininogen 1 Homo sapiens 36-46 10585891-3 1999 In human subcutaneous arteries from uraemic subjects, noradrenaline- and KCl-induced vasoconstrictions were enhanced when nitric oxide (NO) production was blocked with N(G)-nitro-L-arginine methyl ester (L-NAME), but were unaffected by EPO, while acetylcholine- and bradykinin-induced concentration-dependent relaxations were markedly attenuated by L-NAME, but not by EPO. Norepinephrine 54-67 kininogen 1 Homo sapiens 266-276 10027827-0 1999 Bradykinin promotes ischemic norepinephrine release in guinea pig and human hearts. Norepinephrine 29-43 kininogen 1 Homo sapiens 0-10 10027827-1 1999 We previously reported that bradykinin (BK; 1-1000 nM) facilitates norepinephrine (NE) release from cardiac sympathetic nerves. Norepinephrine 67-81 kininogen 1 Homo sapiens 28-38 10027827-1 1999 We previously reported that bradykinin (BK; 1-1000 nM) facilitates norepinephrine (NE) release from cardiac sympathetic nerves. Norepinephrine 67-81 kininogen 1 Homo sapiens 40-42 9383175-1 1997 OBJECTIVE: To investigate the role of angiotensin converting enzyme (ACE) inhibition in bradykinin-mediated modulation of noradrenaline release in human and rat atrium. Norepinephrine 122-135 kininogen 1 Homo sapiens 88-98 9383175-5 1997 In contrast, 0.001-0.1 micromol/l bradykinin enhanced the release of noradrenaline in rat atrium. Norepinephrine 69-82 kininogen 1 Homo sapiens 34-44 9383175-6 1997 In the presence of 3 micromol/l of the ACE inhibitor captopril, however, bradykinin significantly enhanced the release of noradrenaline in human atrium. Norepinephrine 122-135 kininogen 1 Homo sapiens 73-83 9383175-11 1997 CONCLUSION: These data suggest that bradykinin facilitates the release of noradrenaline in human and rat atrium by activation of bradykinin receptors of the B2-subtype and subsequent release of facilitatory prostaglandins. Norepinephrine 74-87 kininogen 1 Homo sapiens 129-139 7833219-5 1994 In this study the effects of a specific inhibitor of nitric oxide synthase, L-NG-monomethyl-arginine (L-NMMA) and noradrenaline on the vasodilator responses to bradykinin were examined in the forearm arterial bed of healthy volunteers. Norepinephrine 114-127 kininogen 1 Homo sapiens 160-170 7833219-12 1994 The response to bradykinin, but not that to GTN, was attenuated by L-NMMA compared with noradrenaline (P < 0.05; n = 6), suggesting that bradykinin-induced vasodilatation in the forearm is mediated, at least in part, by stimulating release of nitric oxide. Norepinephrine 88-101 kininogen 1 Homo sapiens 140-150 8293770-6 1993 Whereas Ang I exerted no facilitating action on noradrenaline, bradykinin stimulated noradrenaline release dose-dependently, almost during converting enzyme inhibition. Norepinephrine 85-98 kininogen 1 Homo sapiens 63-73 1993889-8 1991 Changes in the inositol polyphosphate second messengers are compared with the time course of bradykinin-stimulated increases in free intracellular Ca2+ concentrations and noradrenaline release. Norepinephrine 171-184 kininogen 1 Homo sapiens 93-103 8499491-4 1993 Treatment of the cells with 10(-6) M bradykinin exhausts calcium release such that the successive treatment of the cells with norepinephrine, carbachol, or serotonin results in no secondary response. Norepinephrine 126-140 kininogen 1 Homo sapiens 37-47 8499491-5 1993 In contrast, bradykinin treatment of the cells following exposure to norepinephrine, carbachol, or serotonin caused a secondary increase in calcium release. Norepinephrine 69-83 kininogen 1 Homo sapiens 13-23 2280902-0 1990 Divalent cations effectively replace Ca2+ and support bradykinin induced noradrenaline release. Norepinephrine 73-86 kininogen 1 Homo sapiens 54-64 2280902-3 1990 Alkaline metals, barium (Ba2+), strontium (Sr2+) and other metal cations, manganese (Mn2+) or lanthanum (La3+), support BK-induced [3H]noradrenaline ([3H]NA) release. Norepinephrine 135-148 kininogen 1 Homo sapiens 120-122 3929859-4 1985 Bradykinin is 1,000-fold more potent than the other agonists tested, which include histamine, norepinephrine, epinephrine, eledoisin-related peptide, arginine-vasopressin, lysine-vasopressin, desmopressin acetate, carbachol, and acetylcholine. Norepinephrine 94-108 kininogen 1 Homo sapiens 0-10 7649580-1 1995 The aim of this study was to investigate angiotensin II (Ang II) receptor-, bradykinin receptor-, and beta-adrenergic receptor-mediated modulation of norepinephrine release from human renal sympathetic nerves and to characterize the respective receptor subtypes involved. Norepinephrine 150-164 kininogen 1 Homo sapiens 76-86 3037217-2 1987 In astrocytes, norepinephrine (NE) produced the greatest stimulation with significant increase also observed with bradykinin. Norepinephrine 15-29 kininogen 1 Homo sapiens 114-124