PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20666638-4 2011 Suppressed responsiveness of parvocellular paraventricular nucleus (pPVN) corticotropin-releasing hormone neurons, and hence the HPA axis, following IL-1beta in late pregnancy is evidently explained by presynaptic inhibition of noradrenaline release in the pPVN, owing to increased endogenous opioid peptide enkephalin production in brainstem nucleus tractus solitarii neurons. Norepinephrine 228-241 corticotropin releasing hormone Rattus norvegicus 74-105 21362438-2 2011 We previously demonstrated that the major brain norepinephrine (NE)-containing nucleus, locus coeruleus (LC) is more sensitive to stressors and to the stress-related neuropeptide, corticotropin-releasing factor (CRF) in female compared to male rats. Norepinephrine 48-62 corticotropin releasing hormone Rattus norvegicus 180-210 20519139-2 2010 administered corticotropin-releasing factor (CRF) (0.5-3.0 nmol/animal) dose-dependently elevates plasma noradrenaline and adrenaline through brain phospholipase C-, diacylglycerol lipase- and prostanoids-mediated mechanisms in rats. Norepinephrine 105-118 corticotropin releasing hormone Rattus norvegicus 13-43 20004705-2 2010 It has been suggested that endogenous interleukin-1beta (IL-1beta) is involved in norepinephrine (NE)-induced release of corticotropin-releasing hormone (CRH) from the paraventricular nucleus of the hypothalamus (PVN). Norepinephrine 82-96 corticotropin releasing hormone Rattus norvegicus 121-152 20212497-3 2010 We hypothesized that consumption of an HF diet activates HPA axis by increasing norepinephrine (NE) in the paraventricular nucleus (PVN) of the hypothalamus, leading to elevation in corticotrophin-releasing hormone (CRH) concentration in the median eminence (ME) resulting in elevated serum corticosterone (CORT). Norepinephrine 80-94 corticotropin releasing hormone Rattus norvegicus 182-214 20004705-2 2010 It has been suggested that endogenous interleukin-1beta (IL-1beta) is involved in norepinephrine (NE)-induced release of corticotropin-releasing hormone (CRH) from the paraventricular nucleus of the hypothalamus (PVN). Norepinephrine 82-96 corticotropin releasing hormone Rattus norvegicus 154-157 18445123-3 2008 The catecholaminergic afferents of CRH and TRH neurones originate from both noradrenaline- and adrenaline-synthesising cell groups located in the brainstem, and collectively represent one of the most well studied neural inputs of these neurones. Norepinephrine 76-89 corticotropin releasing hormone Rattus norvegicus 35-38 18423439-2 2008 When corticotropin-releasing factor was given at 0.5, 1.5, and 3.0 nmol/animal intracerebroventricularly, it dose-dependently increased noradrenaline release but not adrenaline release in the hypothalamic paraventricular nucleus. Norepinephrine 136-149 corticotropin releasing hormone Rattus norvegicus 5-35 18423439-4 2008 In addition, the corticotropin-releasing factor-induced elevation of noradrenaline release in the hypothalamic paraventricular nucleus and plasma corticosterone were abolished by hexamethonium, a non-selective nicotinic acetylcholine receptor antagonist, at 1.8 micromol/animal, intracerebroventricularly, and alpha-conotoxin MII, a potent alpha(3)beta(2) nicotinic acetylcholine receptor antagonist, at 30 nmol/animal, i.c.v. Norepinephrine 69-82 corticotropin releasing hormone Rattus norvegicus 17-47 17350615-0 2007 Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats. Norepinephrine 24-37 corticotropin releasing hormone Rattus norvegicus 142-172 17991694-7 2008 Suppressed responsiveness of the CRH neurones, and hence the HPA axis, following IL-1beta in late pregnancy is explained by presynaptic inhibition of noradrenaline release in the pPVN, due to increased endogenous enkephalin and mu-opioid receptor production in brainstem NTS neurones. Norepinephrine 150-163 corticotropin releasing hormone Rattus norvegicus 33-36 17947354-1 2008 Corticotropin-releasing factor (CRF) activates locus coeruleus (LC)-norepinephrine neurons during stress. Norepinephrine 68-82 corticotropin releasing hormone Rattus norvegicus 0-30 18280616-0 2008 Effects of chlordiazepoxide on footshock- and corticotropin-releasing factor-induced increases in cortical and hypothalamic norepinephrine secretion in rats. Norepinephrine 124-138 corticotropin releasing hormone Rattus norvegicus 31-76 16941481-6 2006 The concomitant administration of desipramine (DMI), a specific noradrenaline uptake inhibitor, fully prevented the RIS-induced increase in CRH expression. Norepinephrine 64-77 corticotropin releasing hormone Rattus norvegicus 140-143 17194545-1 2007 Previous studies have shown that corticotropin-releasing factor (CRF), an integral mediator of the stress response, and opioids regulate the activity of the locus-coeruleus-norepinephrine (LC-NE) system during stress in a reciprocal manner. Norepinephrine 173-187 corticotropin releasing hormone Rattus norvegicus 33-63 17100837-0 2006 Corticotropin-releasing factor promotes growth of brain norepinephrine neuronal processes through Rho GTPase regulators of the actin cytoskeleton in rat. Norepinephrine 56-70 corticotropin releasing hormone Rattus norvegicus 0-30 17100837-1 2006 Cognitive aspects of the acute stress response are partly mediated through activation of the locus coeruleus (LC)-norepinephrine (NE) system via corticotropin-releasing factor (CRF). Norepinephrine 114-128 corticotropin releasing hormone Rattus norvegicus 145-175 15833600-4 2005 Although the catecholamines, norepinephrine (NE) and dopamine (DA) are believed to be crucial factors in the stimulation of CRH neurons, it is not clear if they affect the cell bodies or terminals of these neurons to cause HPA activation. Norepinephrine 29-43 corticotropin releasing hormone Rattus norvegicus 124-127 16123744-0 2006 Sexually dimorphic responses of the brain norepinephrine system to stress and corticotropin-releasing factor. Norepinephrine 42-56 corticotropin releasing hormone Rattus norvegicus 78-108 16819988-1 2006 Corticotropin-releasing factor (CRF) acts within the locus coeruleus (LC), to modulate activity of the LC-norepinephrine (NE) system. Norepinephrine 106-120 corticotropin releasing hormone Rattus norvegicus 0-30 14566941-1 2003 Recent evidence suggests that certain stressors release both endogenous opioids and corticotropin-releasing factor (CRF) to modulate activity of the locus coeruleus (LC)-norepinephrine (NE) system. Norepinephrine 170-184 corticotropin releasing hormone Rattus norvegicus 84-114 15305046-5 2004 The intracerebroventricular injection of CRH significantly augmented the content of norepinephrine (NE) in locus coeruleus (LC) of rats, which was significantly suppressed by the intracerebroventricular injection of TMCA. Norepinephrine 84-98 corticotropin releasing hormone Rattus norvegicus 41-44 15120484-0 2004 Regulation of hypoxia-induced release of corticotropin-releasing factor in the rat hypothalamus by norepinephrine. Norepinephrine 99-113 corticotropin releasing hormone Rattus norvegicus 41-71 15385601-0 2004 Chronic morphine sensitizes the brain norepinephrine system to corticotropin-releasing factor and stress. Norepinephrine 38-52 corticotropin releasing hormone Rattus norvegicus 63-93 15385601-4 2004 Chronic morphine selectively sensitized locus ceruleus (LC)-norepinephrine (NE) neurons to corticotropin-releasing factor (CRF), an integral mediator of the stress response. Norepinephrine 60-74 corticotropin releasing hormone Rattus norvegicus 91-121 12706465-8 2003 The vasopressin-induced noradrenaline release from adrenal medulla is mediated by brain thromboxane A(2)-mediated mechanisms, while the CRH-induced noradrenaline release from sympathetic nerves is mediated by brain prostanoid (other than thromboxane A(2))-mediated mechanisms. Norepinephrine 148-161 corticotropin releasing hormone Rattus norvegicus 136-139 14519412-7 2003 administered CRH increased plasma noradrenaline and adrenaline in a dose-dependent manner (0.5, 1.5, and 3.0 nmol/animal). Norepinephrine 34-47 corticotropin releasing hormone Rattus norvegicus 13-16 12706465-2 2003 The present study was designed to characterize the source of plasma noradrenaline induced by centrally administered vasopressin and corticotropin-releasing hormone (CRH) in urethane-anesthetized rats. Norepinephrine 68-81 corticotropin releasing hormone Rattus norvegicus 132-163 14552557-4 2003 Corticoliberin increased dopamine and noradrenaline levels in the hypothalamus of both rat lines, with significant decreases in the striatum. Norepinephrine 38-51 corticotropin releasing hormone Rattus norvegicus 0-14 12690638-5 2003 Since the CVS-induced modulation of CRH levels are consistent with an alteration of tyrosine hydroxylase levels in the locus coeruleus, CRH-norepinephrine (NE) interaction in the terminal projection of forebrain NE systems, PVN, BNST and CeA where NE stimulates CRII release, might contribute to the bi-directional change in CRH. Norepinephrine 140-154 corticotropin releasing hormone Rattus norvegicus 136-139 12706465-2 2003 The present study was designed to characterize the source of plasma noradrenaline induced by centrally administered vasopressin and corticotropin-releasing hormone (CRH) in urethane-anesthetized rats. Norepinephrine 68-81 corticotropin releasing hormone Rattus norvegicus 165-168 12706465-3 2003 Intracerebroventricularly administered vasopressin (0.2 nmol/animal) and CRH (1.5 nmol/animal) elevated plasma levels of noradrenaline and adrenaline. Norepinephrine 121-134 corticotropin releasing hormone Rattus norvegicus 73-76 12690638-5 2003 Since the CVS-induced modulation of CRH levels are consistent with an alteration of tyrosine hydroxylase levels in the locus coeruleus, CRH-norepinephrine (NE) interaction in the terminal projection of forebrain NE systems, PVN, BNST and CeA where NE stimulates CRII release, might contribute to the bi-directional change in CRH. Norepinephrine 140-154 corticotropin releasing hormone Rattus norvegicus 136-139 10686300-7 2000 pre-treatment of rats with alpha-helical CRH significantly reduced the conditioned-fear-induced tachycardiac and ACTH response, and enhanced the increase in PQ interval, without affecting the noradrenaline and adrenaline response. Norepinephrine 192-205 corticotropin releasing hormone Rattus norvegicus 41-44 11938651-4 2002 The CRH administration led to increased dopamine and noradrenaline levels in hypothalamus and decreased those in striatum in rats of both strains, but in KLA the decrease was more evident. Norepinephrine 53-66 corticotropin releasing hormone Rattus norvegicus 4-7 10704782-0 2000 Hippocampal norepinephrine-like voltammetric responses following infusion of corticotropin-releasing factor into the locus coeruleus. Norepinephrine 12-26 corticotropin releasing hormone Rattus norvegicus 77-107 12617949-3 2003 The present study examines whether corticotropin-releasing hormone contributes to stress-evoked increases in extracellular norepinephrine and dopamine in rat medial prefrontal cortex, as monitored by in vivo microdialysis. Norepinephrine 123-137 corticotropin releasing hormone Rattus norvegicus 35-66 12617949-6 2003 Intraventricular administration of 3 microg of D-Phe-corticotropin-releasing hormone attenuated the increase in extracellular norepinephrine induced by co-administration of 3 microg of corticotropin-releasing hormone, confirming the efficacy of this compound. Norepinephrine 126-140 corticotropin releasing hormone Rattus norvegicus 53-84 12617949-6 2003 Intraventricular administration of 3 microg of D-Phe-corticotropin-releasing hormone attenuated the increase in extracellular norepinephrine induced by co-administration of 3 microg of corticotropin-releasing hormone, confirming the efficacy of this compound. Norepinephrine 126-140 corticotropin releasing hormone Rattus norvegicus 185-216 12153469-1 2002 Hypotensive stress engages corticotropin-releasing factor (CRF) release within the rat locus coeruleus (LC), which activates LC neurones, initiating norepinephrine release in forebrain and activation of forebrain electroencephalographic activity. Norepinephrine 149-163 corticotropin releasing hormone Rattus norvegicus 27-57 11517018-1 2001 OBJECTIVE: Stress-induced release of noradrenaline (NA) from locus coeruleus (LC) neurons is mainly regulated by corticotropin-releasing hormone (CRH). Norepinephrine 37-50 corticotropin releasing hormone Rattus norvegicus 113-144 11517018-1 2001 OBJECTIVE: Stress-induced release of noradrenaline (NA) from locus coeruleus (LC) neurons is mainly regulated by corticotropin-releasing hormone (CRH). Norepinephrine 37-50 corticotropin releasing hormone Rattus norvegicus 146-149 11295232-0 2001 Norepinephrine-induced CRH and AVP gene transcription within the hypothalamus: differential regulation by corticosterone. Norepinephrine 0-14 corticotropin releasing hormone Rattus norvegicus 23-26 11295232-1 2001 We have previously demonstrated that microinjection of norepinephrine (NE) into the paraventricular nucleus of the hypothalamus (PVN) of conscious rats elicits a marked increase in CRH gene transcription, indicated by CRH hnRNA levels, without changing AVP hnRNA levels. Norepinephrine 55-69 corticotropin releasing hormone Rattus norvegicus 181-184 11295232-1 2001 We have previously demonstrated that microinjection of norepinephrine (NE) into the paraventricular nucleus of the hypothalamus (PVN) of conscious rats elicits a marked increase in CRH gene transcription, indicated by CRH hnRNA levels, without changing AVP hnRNA levels. Norepinephrine 55-69 corticotropin releasing hormone Rattus norvegicus 218-221 11239906-2 2001 Furthermore, the increase in norepinephrine release in response to the stress-related peptide corticotropin-releasing hormone (CRH) is potentiated by prior chronic stress exposure. Norepinephrine 29-43 corticotropin releasing hormone Rattus norvegicus 94-125 11239906-2 2001 Furthermore, the increase in norepinephrine release in response to the stress-related peptide corticotropin-releasing hormone (CRH) is potentiated by prior chronic stress exposure. Norepinephrine 29-43 corticotropin releasing hormone Rattus norvegicus 127-130 11069122-0 2000 Corticotropin-releasing hormone and arginine vasopressin: mRNA and secretion are differentially regulated according to the pattern of exposure to noradrenaline in rat hypothalamic neurones. Norepinephrine 146-159 corticotropin releasing hormone Rattus norvegicus 0-31 11069122-1 2000 Hypothalamic corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are secreted from the median eminence in a pulsatile manner and regulated by noradrenaline during stress. Norepinephrine 159-172 corticotropin releasing hormone Rattus norvegicus 13-44 11069122-1 2000 Hypothalamic corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are secreted from the median eminence in a pulsatile manner and regulated by noradrenaline during stress. Norepinephrine 159-172 corticotropin releasing hormone Rattus norvegicus 46-49 10700658-3 2000 This effect involves sympathetic nervous system (SNS) activation, since CRH-treatment resulted in a marked increase in plasma norepinephrine (NE) and epinephrine (E), and sympathetic blockade by subcutaneously injected atenolol (1 mg/kg), a beta1-selective adrenergic antagonist, completely prevented the CRH-induced tachycardia. Norepinephrine 126-140 corticotropin releasing hormone Rattus norvegicus 72-75 10421711-0 1999 Discrete local application of corticotropin-releasing factor increases locus coeruleus discharge and extracellular norepinephrine in rat hippocampus. Norepinephrine 115-129 corticotropin releasing hormone Rattus norvegicus 30-60 10560022-0 1999 The role of corticotropin-releasing factor--norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress. Norepinephrine 44-58 corticotropin releasing hormone Rattus norvegicus 12-42 9202305-0 1997 Impact of corticotropin-releasing hormone on extracellular norepinephrine in prefrontal cortex after chronic cold stress. Norepinephrine 59-73 corticotropin releasing hormone Rattus norvegicus 10-41 10069701-1 1998 This study was designed to determine the role of endogenous nitric oxide (NO) in the corticotropin-releasing hormone (CRH)-induced ACTH and corticosterone secretion, as well as possible involvement of hypothalamic dopamine and noradrenaline in that secretion in conscious rats. Norepinephrine 227-240 corticotropin releasing hormone Rattus norvegicus 118-121 9865861-2 1998 infusions of corticotropin-releasing factor (CRF) activate locus coeruleus (LC) noradrenergic neurons and increase the metabolism and extracellular concentrations of norepinephrine (NE) in several brain regions, suggesting increased release. Norepinephrine 166-180 corticotropin releasing hormone Rattus norvegicus 13-43 10377355-0 1999 Differential regulation of corticotropin-releasing hormone and vasopressin gene transcription in the hypothalamus by norepinephrine. Norepinephrine 117-131 corticotropin releasing hormone Rattus norvegicus 27-58 10377355-5 1999 Norepinephrine (NE) is a well known neurotransmitter that regulates CRH neurons in the PVN. Norepinephrine 0-14 corticotropin releasing hormone Rattus norvegicus 68-71 10366021-11 1999 Expression of alpha1D messenger RNA in distinct subsets of cells synthesizing corticotropin-releasing hormone may also help to clarify contradictory and inconsistent observations in the literature regarding the role of norepinephrine in the stress response, and may account for a presumed stressor-specific role for norepinephrine in activation of the hypothalamic-pituitary-adrenal axis. Norepinephrine 219-233 corticotropin releasing hormone Rattus norvegicus 78-109 10366021-11 1999 Expression of alpha1D messenger RNA in distinct subsets of cells synthesizing corticotropin-releasing hormone may also help to clarify contradictory and inconsistent observations in the literature regarding the role of norepinephrine in the stress response, and may account for a presumed stressor-specific role for norepinephrine in activation of the hypothalamic-pituitary-adrenal axis. Norepinephrine 316-330 corticotropin releasing hormone Rattus norvegicus 78-109 8568924-0 1995 Norepinephrine but not epinephrine stimulates the release of corticotropin-releasing factor from in vitro superfused rat hypothalamus. Norepinephrine 0-14 corticotropin releasing hormone Rattus norvegicus 61-91 9112390-3 1997 or into the fourth ventricle, stimulated the release of norepinephrine (NE) into the hypothalamic paraventricular nucleus (PVN), the site of neurons containing CRH. Norepinephrine 56-70 corticotropin releasing hormone Rattus norvegicus 160-163 7664655-2 1995 Alterations in norepinephrine (NE) release, reuptake, and metabolism in the hypothalamic paraventricular nucleus (PVN) could also contribute to dysregulation of the HPA axis in obese Zucker rats via effects on corticotropin-releasing hormone neurons or could be secondary to some other primary defect. Norepinephrine 15-29 corticotropin releasing hormone Rattus norvegicus 210-241 8958787-2 1996 It has been recently reported that noradrenaline (NA), applied within the hypothalamic paraventricular nucleus, suppresses the pulsatile release of LH in the rat through a corticotrophin-releasing hormone (CRH)-dependent mechanism. Norepinephrine 35-48 corticotropin releasing hormone Rattus norvegicus 172-204 8958787-2 1996 It has been recently reported that noradrenaline (NA), applied within the hypothalamic paraventricular nucleus, suppresses the pulsatile release of LH in the rat through a corticotrophin-releasing hormone (CRH)-dependent mechanism. Norepinephrine 35-48 corticotropin releasing hormone Rattus norvegicus 206-209 8003768-0 1994 An interleukin-1 beta-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: an in vivo microdialysis study in conscious rats. Norepinephrine 30-43 corticotropin releasing hormone Rattus norvegicus 87-117 7727801-4 1994 In the corticosterone response to CRH administered icv, a moderate involvement of hypothalamic alpha 1-adrenergic receptors and neuronal noradrenaline seems possible. Norepinephrine 137-150 corticotropin releasing hormone Rattus norvegicus 34-37 7956940-0 1994 Microinjection of norepinephrine into the paraventricular nucleus of the hypothalamus stimulates corticotropin-releasing factor gene expression in conscious rats. Norepinephrine 18-32 corticotropin releasing hormone Rattus norvegicus 97-127 8058208-1 1994 Using the in vivo microdialysis method, we have found that at moderate doses (1.44, 3.6 and 7.2 micrograms), corticotropin-releasing factor (CRF) facilitated norepinephrine (NE) release from the dentate gyrus of hippocampus in rats in a dose-response fashion. Norepinephrine 158-172 corticotropin releasing hormone Rattus norvegicus 109-139 8003768-7 1994 An intracerebroventricular (ICV) injection of a corticotropin-releasing factor (CRF) antagonist (alpha-helical CRF9-41, 30 micrograms) significantly attenuated the IL-1 beta-induced increase in the noradrenaline release. Norepinephrine 198-211 corticotropin releasing hormone Rattus norvegicus 48-78 8351952-2 1993 administration of corticotropin-releasing factor (CRF) antagonist, alpha-helical CRF9-41 (ahCRF) on stress-induced increases in noradrenaline (NA) release in rat brain regions. Norepinephrine 128-141 corticotropin releasing hormone Rattus norvegicus 18-48 8293299-2 1993 administration of corticotropin-releasing factor (CRF) antagonist, alpha-helical CRF9-41 (ahCRF), on increases in noradrenaline (NA) turnover caused by immobilization stress in rat brain regions. Norepinephrine 114-127 corticotropin releasing hormone Rattus norvegicus 18-48 8358534-21 1993 Studies in rats, in which the noradrenaline isomer 6-hydroxydopamine was used, suggested that the post synaptic uptake process is operative in hypothalamic CRH and vasopressin neurones in vivo.11. Norepinephrine 30-43 corticotropin releasing hormone Rattus norvegicus 156-159 8327547-1 1993 The effect of corticotropin-releasing factor (CRF) on central noradrenaline (NA) metabolism was examined by measuring levels of the major metabolite of NA, 3-methoxy-4-hydroxy-phenylethyleneglycol sulfate (MHPG-SO4) in several rat brain regions. Norepinephrine 62-75 corticotropin releasing hormone Rattus norvegicus 14-44 8431775-0 1993 Corticotropin-releasing factor enhances noradrenaline release in the rat hypothalamus assessed by intracerebral microdialysis. Norepinephrine 40-53 corticotropin releasing hormone Rattus norvegicus 0-30 2906518-3 1988 Hypothalamic CRH released from the hypothalamic neuron not only activates the HPA axis, but also stimulates the locus coeruleus-norepinephrine system (LC) and the central sympathetic system (CSS). Norepinephrine 128-142 corticotropin releasing hormone Rattus norvegicus 13-16 1687480-2 1991 In addition, the ICV administration of CRH caused a significant increase in dopamine (DA) and norepinephrine turnover (NE) in various forebrain regions. Norepinephrine 94-108 corticotropin releasing hormone Rattus norvegicus 39-42 8391619-2 1993 To explore whether there is a rapid change in the secretory response of the hypothalamic CRH neuron during acute stress, we report here a study of the effects of KCl and norepinephrine (NE) on CRH release in vitro from rat hypothalami explanted after 5, 30, 60, and 120 minutes of immobilization. Norepinephrine 170-184 corticotropin releasing hormone Rattus norvegicus 193-196 5568-7 1976 Noradrenaline blocked the release of CRH induced by both acetylcholine and 5-hydroxytryptamine and presumably this inhibition was caused by direct action on the CRH neurone. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 37-40 6091416-0 1984 Corticotropin-releasing factor increases noradrenaline turnover in the median eminence and reduces noradrenaline turnover in the paraventricular region of the hypophysectomized male rat. Norepinephrine 41-54 corticotropin releasing hormone Rattus norvegicus 0-30 6091416-0 1984 Corticotropin-releasing factor increases noradrenaline turnover in the median eminence and reduces noradrenaline turnover in the paraventricular region of the hypophysectomized male rat. Norepinephrine 99-112 corticotropin releasing hormone Rattus norvegicus 0-30 7049676-1 1982 Corticotropin-releasing factor (CRF) injected into the brains of rats produces hyperglycemia and an increase in plasma concentrations of glucagon, epinephrine, and norepinephrine. Norepinephrine 164-178 corticotropin releasing hormone Rattus norvegicus 0-30 6298888-8 1982 They also support the suggestion that epinephrine and/or norepinephrine could be involved as physiological corticotropin-releasing factor(s). Norepinephrine 57-71 corticotropin releasing hormone Rattus norvegicus 107-137 38334-9 1979 Acetylcholine-induced increases in hypothalamic CRH production were reduced by GABA, noradrenaline, adrenaline, methoxamine and phenylephrine but not by isoprenaline. Norepinephrine 85-98 corticotropin releasing hormone Rattus norvegicus 48-51 304104-6 1977 Noradrenaline and glycine decreased the spontaneous release of CRH from the hypothalamus but neither of these substances affected hypothalamic CRH content. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 63-66 304104-10 1977 Noradrenaline, GABA and corticosterone reduced the acetylcholine- and 5-HT-induced increases in the release of CRH from the hypothalamus. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 111-114 304104-11 1977 The rises in CRH content induced by acetylcholine and 5-HT were also reduced by noradrenaline and GABA but increased by corticosterone. Norepinephrine 80-93 corticotropin releasing hormone Rattus norvegicus 13-16 5568-7 1976 Noradrenaline blocked the release of CRH induced by both acetylcholine and 5-hydroxytryptamine and presumably this inhibition was caused by direct action on the CRH neurone. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 161-164 32360378-0 2020 Repeated norepinephrine receptor stimulation in the BNST induces sensorimotor gating deficits via corticotropin releasing factor. Norepinephrine 9-23 corticotropin releasing hormone Rattus norvegicus 98-128 1079076-6 1975 Noradrenaline (10 ng), however, was able to inhibit the release of CRH in response to acetylcholine (3 pg) and this action of noradrenaline was reduced by phentolamine (100 ng), an alpha adrenergic blocking agent. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 67-70 1079076-6 1975 Noradrenaline (10 ng), however, was able to inhibit the release of CRH in response to acetylcholine (3 pg) and this action of noradrenaline was reduced by phentolamine (100 ng), an alpha adrenergic blocking agent. Norepinephrine 126-139 corticotropin releasing hormone Rattus norvegicus 67-70 32871155-0 2020 Corticotrophin releasing factor, but not alcohol, modulates norepinephrine release in the rat central nucleus of the amygdala. Norepinephrine 60-74 corticotropin releasing hormone Rattus norvegicus 0-31 23643838-1 2013 Hemodynamic stress via hypotensive challenge has been shown previously to cause a corticotropin-releasing factor (CRF)-mediated increase in tonic locus coeruleus (LC) activity and consequent release of norepinephrine (NE) in noradrenergic terminal fields. Norepinephrine 202-216 corticotropin releasing hormone Rattus norvegicus 82-112 21993205-0 2012 Corticotropin-releasing factor in the norepinephrine nucleus, locus coeruleus, facilitates behavioral flexibility. Norepinephrine 38-52 corticotropin releasing hormone Rattus norvegicus 0-30 21993205-1 2012 Corticotropin-releasing factor (CRF), the stress-related neuropeptide, acts as a neurotransmitter in the brain norepinephrine nucleus, locus coeruleus (LC), to activate this system during stress. Norepinephrine 111-125 corticotropin releasing hormone Rattus norvegicus 0-30 31560870-0 2019 Prostaglandin E2 receptor EP3 subtype in the paraventricular hypothalamic nucleus mediates corticotropin-releasing factor-induced elevation of plasma noradrenaline levels in rats. Norepinephrine 150-163 corticotropin releasing hormone Rattus norvegicus 91-121 25359531-0 2015 Injection of corticotropin-releasing hormone into the amygdala aggravates visceral nociception and induces noradrenaline release in rats. Norepinephrine 107-120 corticotropin releasing hormone Rattus norvegicus 13-44 25359531-3 2015 Here, we verified the hypothesis that CRH in the CeA sensitizes visceral nociception via CRH-R1 with release of noradrenaline, dopamine, and serotonin (5-HT) in the CeA. Norepinephrine 112-125 corticotropin releasing hormone Rattus norvegicus 38-41 25359531-9 2015 Noradrenaline in the CeA was increased by CRD, further increased by CRH, and inhibited by CRH-R1 antagonist. Norepinephrine 0-13 corticotropin releasing hormone Rattus norvegicus 68-71 25359531-12 2015 CONCLUSIONS & INFERENCES: These results suggest that CRH in the CeA sensitizes visceral nociception via CRH-R1 with release of noradrenaline. Norepinephrine 131-144 corticotropin releasing hormone Rattus norvegicus 57-60 22510725-2 2012 The neuropeptide, corticotropin-releasing factor (CRF), coordinates the physiological and behavioral responses to stress, in part, by activating the locus coeruleus-norepinephrine (LC-NE) projection system. Norepinephrine 165-179 corticotropin releasing hormone Rattus norvegicus 18-48 22210331-0 2012 Predator stress engages corticotropin-releasing factor and opioid systems to alter the operating mode of locus coeruleus norepinephrine neurons. Norepinephrine 121-135 corticotropin releasing hormone Rattus norvegicus 24-54 22210331-1 2012 The norepinephrine nucleus, locus coeruleus (LC), has been implicated in cognitive aspects of the stress response, in part through its regulation by the stress-related neuropeptide, corticotropin-releasing factor (CRF). Norepinephrine 4-18 corticotropin releasing hormone Rattus norvegicus 182-212