PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35099408-7 2022 Time-course assay showed that stimulation of oral SCC cells with norepinephrine decreased the cleavage of caspase-3 and expression of MDR-1 but only transiently affected ABCG2 expression. Norepinephrine 65-79 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 170-175 35099408-10 2022 Expressions of ABCG2, and p-Akt but not of MDR-1, were enhanced by norepinephrine plus cisplatin when compared to cisplatin only in both cell lines. Norepinephrine 67-81 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 15-20 35099408-12 2022 These findings reveal for the first time that stress hormone norepinephrine induce resistance of oral cancer cells to cisplatin in vitro through the ADRB/Akt/ABCG2 pathway, pumping the drug out of the cell and inhibiting apoptosis. Norepinephrine 61-75 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 158-163