PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35550600-4 2022 We developed NOVOSIS putty (NP), a novel composite material of hydroxyapatite (HA), beta-tricalcium phosphate (beta-TCP)/hydrogel, and BMP-2, which can sustainably release BMP-2 over 2 weeks. beta-tricalcium phosphate 84-109 bone morphogenetic protein 2 Rattus norvegicus 172-177 35550600-4 2022 We developed NOVOSIS putty (NP), a novel composite material of hydroxyapatite (HA), beta-tricalcium phosphate (beta-TCP)/hydrogel, and BMP-2, which can sustainably release BMP-2 over 2 weeks. beta-tricalcium phosphate 111-119 bone morphogenetic protein 2 Rattus norvegicus 172-177 33113818-6 2020 The results showed that in each four groups (Collagen alone group, Matrigel alone group, Collagen + BMP group and Matrigel + BMP-2), vigorous bone formation was observed on the vertical beta-TCP compared with horizontal beta-TCP. beta-tricalcium phosphate 186-194 bone morphogenetic protein 2 Rattus norvegicus 125-130 33883043-4 2021 RESULTS: The sequential processes of brown algae-inspired biosilicification and collagen coating on the surface of beta-TCP enable the effective incorporation of BMP-2 into the coating layer without losing its bioactivity. beta-tricalcium phosphate 115-123 bone morphogenetic protein 2 Rattus norvegicus 162-167 33125972-8 2020 RT-qPCR analysis show that Asp-Sr/beta-TCP, beta-TCP group and Sr/beta-TCP group showed increased BMP2, Smad1, OPG than the OVX group(p < 0.05), while Asp-Sr/beta-TCP exhibited decreased TNF-alpha IFN-gamma and RANKL than the OVX group(p < 0.05). beta-tricalcium phosphate 44-52 bone morphogenetic protein 2 Rattus norvegicus 98-102 30784943-0 2019 The fast degradation of beta-TCP ceramics facilitates healing of bone defects by the combination of BMP-2 and Teriparatide. beta-tricalcium phosphate 24-32 bone morphogenetic protein 2 Rattus norvegicus 100-105 28389833-0 2017 Immunohistochemistry evaluation of BMP-2 with beta-tricalcium phosphate matrix, polylactic and polyglycolic acid gel, and calcium phosphate cement in rats. beta-tricalcium phosphate 46-71 bone morphogenetic protein 2 Rattus norvegicus 35-40 28256366-0 2017 Bone morphogenetic protein-2 loaded poly(D,L-lactide-co-glycolide) microspheres enhance osteogenic potential of gelatin/hydroxyapatite/beta-tricalcium phosphate cryogel composite for alveolar ridge augmentation. beta-tricalcium phosphate 135-160 bone morphogenetic protein 2 Rattus norvegicus 0-28 28256366-3 2017 This study introduced a novel treatment strategy by infusing poly(D,L-lactide-co-glycolide) (PLGA) microspheres encapsulating bone morphogenetic protein-2 (BMP-2) within a gelatin/hydroxyapatite/beta-tricalcium phosphate (gelatin/HA/beta-TCP) cryogel composite to facilitate supra-alveolar ridge augmentation. beta-tricalcium phosphate 195-220 bone morphogenetic protein 2 Rattus norvegicus 156-161 28256366-3 2017 This study introduced a novel treatment strategy by infusing poly(D,L-lactide-co-glycolide) (PLGA) microspheres encapsulating bone morphogenetic protein-2 (BMP-2) within a gelatin/hydroxyapatite/beta-tricalcium phosphate (gelatin/HA/beta-TCP) cryogel composite to facilitate supra-alveolar ridge augmentation. beta-tricalcium phosphate 233-241 bone morphogenetic protein 2 Rattus norvegicus 156-161 28256366-10 2017 CONCLUSION: BMP-2 loaded PLGA microspheres effectively promoted osteogenic potential of the gelatin/HA/beta-TCP composite and facilitated supra-alveolar ridge augmentation in vivo. beta-tricalcium phosphate 103-111 bone morphogenetic protein 2 Rattus norvegicus 12-17 25783748-9 2017 At 6 weeks, the critical-sized defect in 33% of the rats treated with the Ad-BMP-2-transduced hBMSCs/betaTCP scaffolds was radiographically bridged. beta-tricalcium phosphate 101-108 bone morphogenetic protein 2 Rattus norvegicus 77-82 28262327-1 2017 This study aimed to assess the biological response of BMP-2 (bone morphogenetic protein-2) in supplementation with beta-tricalcium phosphate (TCP) as a carrier in the bone healing of surgical defects in rats" calvaria. beta-tricalcium phosphate 115-140 bone morphogenetic protein 2 Rattus norvegicus 54-59 28262327-1 2017 This study aimed to assess the biological response of BMP-2 (bone morphogenetic protein-2) in supplementation with beta-tricalcium phosphate (TCP) as a carrier in the bone healing of surgical defects in rats" calvaria. beta-tricalcium phosphate 115-140 bone morphogenetic protein 2 Rattus norvegicus 61-89 28262327-1 2017 This study aimed to assess the biological response of BMP-2 (bone morphogenetic protein-2) in supplementation with beta-tricalcium phosphate (TCP) as a carrier in the bone healing of surgical defects in rats" calvaria. beta-tricalcium phosphate 142-145 bone morphogenetic protein 2 Rattus norvegicus 54-59 28262327-5 2017 The supplementation with BMP-2 promoted faster TCP remodeling; however, there was no statistically significant difference for the bone formed in both groups (P>0.05). beta-tricalcium phosphate 47-50 bone morphogenetic protein 2 Rattus norvegicus 25-30 19581707-0 2009 BMP-2 release and dose-response studies in hydroxyapatite and beta-tricalcium phosphate. beta-tricalcium phosphate 62-87 bone morphogenetic protein 2 Rattus norvegicus 0-5 23596469-9 2013 BMP-2/beta-TCP composites showed a trend of increased stiffness compared with the controls (beta-TCP without protein). beta-tricalcium phosphate 92-100 bone morphogenetic protein 2 Rattus norvegicus 0-5 22778550-6 2012 These results demonstrated that it was advantageous to construct tissue engineering bone using ADSCs cotransfected with BMP2 and BMP7 on beta-TCP, providing a potential way for treating bone defects. beta-tricalcium phosphate 137-145 bone morphogenetic protein 2 Rattus norvegicus 120-124 21376389-0 2011 The effect of BMP-2 on the osteoconductive properties of beta-tricalcium phosphate in rat calvaria defects. beta-tricalcium phosphate 57-82 bone morphogenetic protein 2 Rattus norvegicus 14-19 19966384-9 2009 The BMP-2+Dex could significantly promote osteogenic differentiation of RDFCs on beta-TCP. beta-tricalcium phosphate 81-89 bone morphogenetic protein 2 Rattus norvegicus 4-9 18987021-1 2009 We examine the osteogenicity of a sponge biomaterial consisting of a biodegradable mixture of gelatin and beta-tricalcium phosphate (betaTCP) that bound bone morphogenetic protein 2 (BMP-2) in critical-sized bone defects in rats. beta-tricalcium phosphate 106-131 bone morphogenetic protein 2 Rattus norvegicus 153-181 18987021-1 2009 We examine the osteogenicity of a sponge biomaterial consisting of a biodegradable mixture of gelatin and beta-tricalcium phosphate (betaTCP) that bound bone morphogenetic protein 2 (BMP-2) in critical-sized bone defects in rats. beta-tricalcium phosphate 106-131 bone morphogenetic protein 2 Rattus norvegicus 183-188 18987021-1 2009 We examine the osteogenicity of a sponge biomaterial consisting of a biodegradable mixture of gelatin and beta-tricalcium phosphate (betaTCP) that bound bone morphogenetic protein 2 (BMP-2) in critical-sized bone defects in rats. beta-tricalcium phosphate 133-140 bone morphogenetic protein 2 Rattus norvegicus 153-181 18987021-1 2009 We examine the osteogenicity of a sponge biomaterial consisting of a biodegradable mixture of gelatin and beta-tricalcium phosphate (betaTCP) that bound bone morphogenetic protein 2 (BMP-2) in critical-sized bone defects in rats. beta-tricalcium phosphate 133-140 bone morphogenetic protein 2 Rattus norvegicus 183-188 19581707-3 2009 The amount of BMP-2 remaining in the beta-TCP at 1 day after implantation was 49.6%, while the amount was 34.0% in the HAp. beta-tricalcium phosphate 37-45 bone morphogenetic protein 2 Rattus norvegicus 14-19 19581707-7 2009 These results indicate that the absorbable beta-TCP block may be an effective bioceramic for bone induction to deliver BMP-2 to the site of action. beta-tricalcium phosphate 43-51 bone morphogenetic protein 2 Rattus norvegicus 119-124 16362458-6 2005 The second part of the study applied BMP2 gene-modified autologous MSCs/beta-tricalcium phosphate for repair of bone defects in aged rats with positive results. beta-tricalcium phosphate 72-97 bone morphogenetic protein 2 Rattus norvegicus 37-41 15763265-0 2005 Enhanced osteoinduction by controlled release of bone morphogenetic protein-2 from biodegradable sponge composed of gelatin and beta-tricalcium phosphate. beta-tricalcium phosphate 128-153 bone morphogenetic protein 2 Rattus norvegicus 49-77 15763265-1 2005 Biodegradable gelatin sponges at different contents of beta-tricalcium phosphate (beta-TCP) were fabricated to allow bone morphogenetic protein (BMP)-2 to incorporate into them. beta-tricalcium phosphate 82-90 bone morphogenetic protein 2 Rattus norvegicus 117-151 15763265-6 2005 When the osteoinduction activity of gelatin or gelatin-beta-TCP sponges incorporating BMP-2 was studied following the implantation into the back subcutis of rats in terms of histological and biochemical examinations, homogeneous bone formation was histologically observed throughout the sponges, although the extent of bone formation was higher in the sponges with the lower contents of beta-TCP. beta-tricalcium phosphate 55-63 bone morphogenetic protein 2 Rattus norvegicus 86-91