PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22067624-14 2012 CONCLUSIONS: Mild hypothermia reduces the systemic clearances of fentanyl and midazolam in rats after cardiac arrest through alterations in cytochrome P450 3a2 metabolic capacity rather than enzyme affinity as observed with other cytochrome P450s. Fentanyl 65-73 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 140-159