PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31967515-3 2020 Results: Patients in the fentanyl group with the COMT high-pain sensitivity haplotype required less postoperative morphine compared with the average-pain sensitivity haplotype (19.4 [16.5; 23.0] vs 34.6 [26.2; 41.4]; p = 0.00768), but not to the low-pain sensitivity group (30.1 [19.1; 37.7]; p = 0.13). Fentanyl 25-33 catechol-O-methyltransferase Homo sapiens 49-53 25532715-0 2015 COMT gene haplotypes are closely associated with postoperative fentanyl dose in patients. Fentanyl 63-71 catechol-O-methyltransferase Homo sapiens 0-4 25532715-10 2015 COMT gene haplotypes combined by COMT rs6269, rs4633, rs4818, and rs4680, however, significantly affected fentanyl consumption at 24 (P = 0.029) and 48 (P = 0.032) hours after surgery. Fentanyl 106-114 catechol-O-methyltransferase Homo sapiens 0-4 25532715-10 2015 COMT gene haplotypes combined by COMT rs6269, rs4633, rs4818, and rs4680, however, significantly affected fentanyl consumption at 24 (P = 0.029) and 48 (P = 0.032) hours after surgery. Fentanyl 106-114 catechol-O-methyltransferase Homo sapiens 33-37 25532715-11 2015 Among the haplotypes of COMT gene, patients with haplotype ACCG consumed more fentanyl than GCGG and ATCA haplotypes during the first 24 and 48 hours (all P < 0.042) after surgery. Fentanyl 78-86 catechol-O-methyltransferase Homo sapiens 24-28 25532715-13 2015 CONCLUSIONS: COMT gene haplotype constructed by rs6269, rs4633, rs4818, and rs4680 contributes to the individual variation of postoperative analgesia with fentanyl. Fentanyl 155-163 catechol-O-methyltransferase Homo sapiens 13-17 23302985-0 2013 The effect of OPRM1 and COMT genotypes on the analgesic response to intravenous fentanyl labor analgesia. Fentanyl 80-88 catechol-O-methyltransferase Homo sapiens 24-28