PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29256293-1	2018	The first phase of molecular brain imaging of microglial activation in neuroinflammatory conditions began some 20 years ago with the introduction of [11C]-( R)-PK11195, the prototype isoquinoline ligand for translocator protein (18 kDa) (TSPO).	isoquinoline	183-195	translocator protein	Homo sapiens	207-236	
24900292-2	2011	PK 11195, an isoquinoline analogue, is one of the ligands of highest TSPO binding affinity.	isoquinoline	13-25	translocator protein	Homo sapiens	69-73	
7542903-3	1995	Peripheral BZ receptors (PBR) are composed of three subunits: an isoquinoline binding site, a voltage-dependent anion channel, and an adenine nucleotide carrier, with molecular weights of 18, 32, and 30 kDa, respectively.	isoquinoline	65-77	translocator protein	Homo sapiens	0-23	
7542903-3	1995	Peripheral BZ receptors (PBR) are composed of three subunits: an isoquinoline binding site, a voltage-dependent anion channel, and an adenine nucleotide carrier, with molecular weights of 18, 32, and 30 kDa, respectively.	isoquinoline	65-77	translocator protein	Homo sapiens	25-28	
20936410-5	2011	RESULTS: The image contrast and the binding of [(11)C]SSR180575 are higher than that obtained with the isoquinoline-based TSPO radioligand, [(11)C]PK11195.	isoquinoline	103-115	translocator protein	Homo sapiens	122-126	
16842193-6	2006	Subsequent conformationally restrained isoquinoline and indoleacetamide analogues have been synthesised in an attempt to yield PBR ligands with superior affinity and brain kinetics.	isoquinoline	39-51	translocator protein	Homo sapiens	127-130	
9527511-10	1997	These studies demonstrate that the isoquinoline and benzodiazepine sites on the peripheral-type benzodiazepine receptor in human brain manifest many pharmacological characteristics that are distinct from each other and from rodent brain peripheral-type benzodiazepine receptors.	isoquinoline	35-47	translocator protein	Homo sapiens	80-119	
2821259-6	1987	The R-(-) stereoisomer 11b was observed to be approximately 2.5-fold more potent than its enantiomer 11c; this is the first report of stereoselectivity in the isoquinoline series of ligands selective for the PBR.	isoquinoline	159-171	translocator protein	Homo sapiens	208-211