PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22111927-4 2011 A potent and highly selective isoquinoline CHK1 inhibitor (SAR-020106) was identified, which potentiated the efficacies of irinotecan and gemcitabine in SW620 human colon carcinoma xenografts in nude mice. isoquinoline 30-42 checkpoint kinase 1 Homo sapiens 43-47