PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10364850-2 1999 The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay in human hepatoma cells. isoquinoline 75-87 JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens 169-173