PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1354618-2 1992 A single oral dose of bunazosin 2.0 mg caused a significant reduction (P less than 0.05) in urinary sodium excretion after 0-2 h, 2-4 h, and 4-6 h. The mean values for plasma ANP, AVP, aldosterone, and cortisol concentrations at those times were similar after placebo and bunazosin, and plasma renin activity was significantly increased 2 and 4 h after bunazosin. bunazosin 22-31 renin Homo sapiens 294-299