PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12619182-6 2003 In the alendronate treated group, statistically significant changes occurred in the levels of serum IL-1alpha and IL-6 after three months, and in IL-1beta, IL-6, IL-6r and TNF-alpha after six months (p < 0.05). Alendronate 7-18 interleukin 1 alpha Homo sapiens 100-109 10555884-5 1999 RESULTS: A significant decrease of IL-1, IL-6, TNF-alpha, and beta2m was observed after 30 days, persisting after 90 days in the AL group, but with no significant variation in the placebo group. Alendronate 129-131 interleukin 1 alpha Homo sapiens 35-39 34075628-10 2021 (iv) Ale increased or tended to increase various cytokines, and LPS augmented these effects, especially that on IL-1beta. Alendronate 5-8 interleukin 1 alpha Homo sapiens 112-120