PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31448845-4 2020 Functional analyses of recombinant-purified CRAT proteins demonstrated that both missense variants, located in the acyl-group binding site of the enzyme, severely impair its catalytic function toward acetyl-CoA, and the p.Val569Met variant also toward propionyl-CoA and octanoyl-CoA. octanoyl-coenzyme A 270-282 carnitine O-acetyltransferase Homo sapiens 44-48