PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19605405-7 2009 Proteomic analysis identified proline, glutamic acid, and leucine rich protein 1 (PELP1) as a DACH1-binding protein. Proline 30-37 proline, glutamate and leucine rich protein 1 Homo sapiens 82-87 19048289-1 2009 Proline-, glutamic acid-, and leukine-rich protein (PELP1) is a novel co-regulatory protein that modulates genomic and non genomic actions of estrogen receptors. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 52-57 18571832-2 2008 PELP1 contains ten nuclear receptor-interacting boxes (LXXLL motifs), which allow it to interact with ER and other nuclear hormone receptors, a zinc finger, a glutamic acid-rich domain, and two proline-rich domains. Proline 194-201 proline, glutamate and leucine rich protein 1 Homo sapiens 0-5 18571832-3 2008 The proline-rich regions contain several consensus PXXP motifs, which allow PELP1 to couple the ER with SH3 domain-containing kinase signaling proteins, such as Src and PI3K P85 regulatory subunit. Proline 4-11 proline, glutamate and leucine rich protein 1 Homo sapiens 76-81 17545633-1 2007 Proline-, glutamic acid-, leucine-rich protein 1 (PELP1), a novel nuclear receptor coactivator, and its expression is deregulated in hormone-dependent cancers, including those of the breast, endometrium, and ovary. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 50-55 18505929-1 2008 PELP1 (proline-rich, glutamic acid-rich, and leucine-rich protein-1) is a potential proto-oncogene that functions as a coregulator of estrogen receptor (ER), and its expression is deregulated during breast cancer progression. Proline 7-14 proline, glutamate and leucine rich protein 1 Homo sapiens 0-5 27881676-0 2017 Cytoplasmic Localization of Proline, Glutamic Acid, Leucine-rich Protein 1 (PELP1) Induces Breast Epithelial Cell Migration through Up-regulation of Inhibitor of kappaB Kinase epsilon and Inflammatory Cross-talk with Macrophages. Proline 28-35 proline, glutamate and leucine rich protein 1 Homo sapiens 76-81 17525794-1 2007 Proline-, glutamic acid-, and leucine-rich protein (PELP)1, also known as modulator of nongenomic actions of the estrogen receptor (MNAR), is a novel nuclear receptor coregulator with a multitude of functions. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 52-58 17525794-1 2007 Proline-, glutamic acid-, and leucine-rich protein (PELP)1, also known as modulator of nongenomic actions of the estrogen receptor (MNAR), is a novel nuclear receptor coregulator with a multitude of functions. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 132-136 11481323-2 2001 We report the characterization of a new NR coregulator: proline-, glutamic acid-, leucine-rich protein 1 (PELP1), a novel human protein that comprises 1,282 amino acids and is localized on chromosome 17. Proline 56-63 proline, glutamate and leucine rich protein 1 Homo sapiens 106-111 11481323-3 2001 The primary structure of PELP1 consists of several motifs present in most transcriptional regulators including nine NR-interacting boxes (LXXLL motifs), a zinc finger, and glutamic acid- and proline-rich regions. Proline 191-198 proline, glutamate and leucine rich protein 1 Homo sapiens 25-30 34774800-2 2022 Proline, Glutamic acid, and Leucine- rich Protein (PELP1) is a novel nuclear receptor co-regulator that signals across diverse signaling networks and its expression is altered in several cancers. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 51-56 32037484-1 2020 Proline-, glutamic acid-, leucine-rich protein 1 (PELP1) is a novel estrogen receptor (ER) coregulator, demonstrated distinctive characters from other ERalpha coregulators, and has been suggested to be involved in metastasis of several cancers. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 50-55 27881676-1 2017 Cytoplasmic localization of proline, glutamic acid, leucine-rich protein 1 (PELP1) is observed in ~40% of women with invasive breast cancer. Proline 28-35 proline, glutamate and leucine rich protein 1 Homo sapiens 76-81 26472563-3 2015 Proline, glutamic acid, leucine rich protein 1 (PELP1) is a novel steroidal receptor co-regulator, functioning as an oncogene and its expression is maintained in estrogen receptor (ER) negative breast cancers. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 48-53 25789479-3 2015 Prior studies have shown that cytoplasmic proline, glutamic acid and leucine rich protein 1 (PELP1) promotes Tam resistance in breast cancer cell lines. Proline 42-49 proline, glutamate and leucine rich protein 1 Homo sapiens 93-98 26211588-0 2015 Increased expression of proline-, glutamic acid- and leucine-rich protein PELP1 in non-small cell lung cancer. Proline 24-31 proline, glutamate and leucine rich protein 1 Homo sapiens 74-79 24752897-5 2014 Here, we identify proline, glutamic acid, and leucine-rich protein 1 (PELP1), a chromatin-associated factor and transcriptional coregulator, as a ligand-independent macrodomain-interacting factor. Proline 18-25 proline, glutamate and leucine rich protein 1 Homo sapiens 70-75 23975430-2 2014 PELP1 (proline, glutamic acid and leucine rich protein 1) is a nuclear receptor coregulator that is upregulated during breast cancer progression to metastasis and is an independent prognostic predictor of shorter survival of breast cancer patients. Proline 7-14 proline, glutamate and leucine rich protein 1 Homo sapiens 0-5 22403175-3 2012 Our data indicate that E2 induces the formation of a complex between androgen receptor (AR), ERbeta, and a proline-, glutamic acid-, and leucine-rich cofactor protein 1 (PELP1) in PCa cells. Proline 107-114 proline, glutamate and leucine rich protein 1 Homo sapiens 170-175 22992812-1 2012 Proline-, glutamic acid- and leucine-rich protein-1/modulator of non-genomic activity of estrogen receptor (ER) (PELP1/MNAR) is a novel nuclear receptor (NR) co-activator that plays an essential role in the actions of ER. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 125-130 22992812-1 2012 Proline-, glutamic acid- and leucine-rich protein-1/modulator of non-genomic activity of estrogen receptor (ER) (PELP1/MNAR) is a novel nuclear receptor (NR) co-activator that plays an essential role in the actions of ER. Proline 0-7 proline, glutamate and leucine rich protein 1 Homo sapiens 131-135 22812534-1 2012 INTRODUCTION: The estrogen receptor (ER) co-regulator proline glutamic acid and leucine-rich protein 1 (PELP1) is a proto-oncogene that modulates epigenetic changes on ER target gene promoters via interactions with lysine-specific histone demethylase 1 (KDM1). Proline 54-61 proline, glutamate and leucine rich protein 1 Homo sapiens 104-109 21421858-3 2011 In this study, we examined whether the nuclear receptor coregulator PELP1 (proline-, glutamic acid-, leucine-rich protein-1) contributes to progression and metastatic potential of ovarian cancer cells and determined whether blocking of the PELP1 signaling axis had a therapeutic effect. Proline 75-82 proline, glutamate and leucine rich protein 1 Homo sapiens 68-73 21695158-1 2011 BACKGROUND: Proline-, glutamic acid-, and leucine-rich protein (PELP1) is a novel nuclear receptor coregulator with a multitude of functions. Proline 12-19 proline, glutamate and leucine rich protein 1 Homo sapiens 64-69 20442285-6 2010 We also found that TTLL4 expression was correlated with polyglutamylation levels of a glutamate stretch region of the proline, glutamate, and leucine-rich protein 1 (PELP1) that was shown to interact with various proteins such as histone H3, and was involved in several signaling pathways through its function as a scaffold protein. Proline 118-125 proline, glutamate and leucine rich protein 1 Homo sapiens 166-171